Abstract: A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Abstract: The present invention pertains to certain nucleic acid analogs and related kits that are useful for the capture, recognition, detection, identification, or quantification of certain chemical or biological entities.

Abstract: Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.

Abstract: A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Abstract: A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Abstract: A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Abstract: The present invention relates a method for optical storage of information using materials comprising compound having at least two chromophores and a linkage connecting the chromophores. The optical storage method can be effected by use of light having a wavelength of from 100-1600 nm. The compound applicable for the method are typically dimers based on a skeleton made of peptides or amino acids, or alternatively peptide nucleic acid (PNA). The chromophores may thymine, N—(C1-6-alkyl)-thymine, anthracene, acridizinium salts, tetracene, etc.

Abstract: A novel class of compounds, known as peptide nucleic acids, form double-stranded structures with one another and with ssDNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

Abstract: An apparatus for taking a sample of a toxic and/or radioactive substance by ntroducing such substance into a sample vessel. The apparatus includes a rotatable cylinder containing a recess for receiving a sample vessel. A drive shaft is connected to the cylinder for imparting rotary and axial movements to the cylinder for moving the recess of the cylinder between first and second positions. A needle head filling system is arranged above the cylinder at the first position for filling a sample vessel with toxic and/or radioactive substances. The cylinder is lifted by the shaft for engagement with the needle head filling system when being filled and lowered by the shaft after being filled. An inlet and outlet conduit is provided having one end for receiving from and discharging into the recess of the cylinder a sample vessel, the one end being located above the cylinder at the second position.

Abstract: In the manufacture of cylindrical tubes for containers, a foil web and at least one fibre web are helically wound on a heated, rotating mandril. The foil web is wider than the fibre web and its edges lie outside the long edges of the fibre web. The foil web and the fibre web are fed in to the mandril at an angle such that the free edges of the foil web are placed against each other and welded together.

Abstract: A container sleeve 1 having an inner coating 5 of a heat weldable plastics material is fitted with a closure element 2 having a collar 4 of meltable plastics material. The assembly is rotated while a hot welding shoe 35 is inserted through the open end of the sleeve and brought to bear against the collar, which melts the latter and fuses it to the tackified coating 5 to thereby provide a tightly sealed joint.

Abstract: In the bonding of two webs, each having a polyolefin resin surface thereon, to form a laminate the polyolefin surface of a first of said webs is heated to a temperature at which the resin will melt or become tacky, while the polyolefin surface of the second of said webs is heated to a given temperature. The heated surfaces are then brought together in a manner to form a substantially permanent bond therebetween. One advantage of the method is that extremely thick high-density plastic foils can be bonded successfully to fibrous carriers.

Abstract: Apparatus for manufacturing cylindrical tubes from paper or similar fibrous materials. A layer of plastics material which becomes tacky when heated provided on a paper web is heated through the paper web then pressed against a plastics foil web with one edge of the plastics foil web extending beyond the corresponding edge of the paper web. The joined webs are wound helically onto a mandril with the extended edge of the plastics foil web overlapping a corresponding opposite second edge of the plastics foil web. A string of molten adhesive is applied along the extended edge on the mandril. The mandril is cooled to maintain the foil layer nearest the mandril below its melting temperature.

Abstract: The present invention relates to a method of manufacturing from paper and other similar fibrous materials cylindrical tubes comprising an inner, dense, liquid-tight plastics foil layer, in which method at least one paper web and a plastics foil web are wound helically together on a rotating mandril with the plastics foil web located against the forming surface of the mandril, and in which the plastics foil web is bonded to the paper web by means of an adhesive. The invention also relates to an apparatus for carrying out the method.