Patents by Inventor Rolf Beume

Rolf Beume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Roflumilast for the treatment of pulmonary hypertension
    Patent number: 8648100
    Abstract: The invention relates to the use of Roflumilast, Roflumilast N-Oxide or a pharmaceutically acceptable salt of either for the treatment of pulmonary hypertension. The invention additionally relates to the use of Roflumilast, Roflumilast N-oxide or a pharmaceutically acceptable salt of either in combination with a PDE5 inhibitor or a pharmaceutically acceptable salt thereof for the treatment of pulmonary hypertension.
    Type: Grant
    Filed: April 12, 2006
    Date of Patent: February 11, 2014
    Assignee: Takeda GmbH
    Inventors: Rolf Beume, Armin Hatzelmann, Degenhard Marx, Christian Schudt, Hermann Tenor, Saadia Eddahibi, Serge Adnot
  • Roflumilast for the Treatment of Pulmonary Hypertension
    Publication number: 20090215836
    Abstract: The invention relates to the use of Roflumilast, Roflumilast N-Oxide or a pharmaceutically acceptable salt of either for the treatment of pulmonary hypertension. The invention additionally relates to the use of Roflumilast, Roflumilast N-oxide or a pharmaceutically acceptable salt of either in combination with a PDE5 inhibitor or a pharmaceutically acceptable salt thereof for the treatment of pulmonary hypertension.
    Type: Application
    Filed: April 12, 2006
    Publication date: August 27, 2009
    Applicant: NYCOMED GMBH
    Inventors: Rolf Beume, Armin Hatzelmann, Degenhard Marx, Christian Schudt, Hermann Tenor, Saadia Eddahibi, Serge Adnot
  • Use of Roflumilast for the Prophylaxis or Treatment of Emphysema
    Publication number: 20070254928
    Abstract: The invention relates to the use of roflumilast for the prophylaxis of or the treatment of emphysema.
    Type: Application
    Filed: May 4, 2005
    Publication date: November 1, 2007
    Applicant: Altana Pharma AG
    Inventors: Stefan-Lutz Wollin, Rolf Beume, Giuseppe Lungarella, Piero Martorana
  • Synergistic combination comprising roflumilast and (r,r) - formoterol
    Publication number: 20060199865
    Abstract: The invention relates to the combined administration of roflumilast and R,R-formoterol for the treatment of respiratory tract disorders.
    Type: Application
    Filed: November 26, 2003
    Publication date: September 7, 2006
    Inventors: Rolf Beume, Christian Weimar, Degenhard Marx, Daniela Bundschuh, Stefan-Lutz Wollin
  • Synergistic combination comprising roflumilast and formoterol
    Publication number: 20060142308
    Abstract: The invention relates to the combined administration of roflumilast and formoterol for the treatment of respiratory tract disorders.
    Type: Application
    Filed: November 26, 2003
    Publication date: June 29, 2006
    Applicant: Atlanta Pharma AG
    Inventors: Norbert Kolassa, Christian Weimar, Daniela Bundschuh, Rolf Beume, Degenhard Marx
  • Pharmaceutical composition of a pde4 or pde 3/4 inhibitor and histamine receptor antagonist
    Publication number: 20050112069
    Abstract: The invention relates to the combined administration of PDE4 or PDE3/4 inhibitors and histamine receptor antagonists for the treatment of respiratory diseases.
    Type: Application
    Filed: February 25, 2003
    Publication date: May 26, 2005
    Inventors: Rolf Beume, Daniela Bundschuh, Christian Weimar, Stefan-Lutz Wollin
  • Combination
    Publication number: 20050014762
    Abstract: The invention relates to the combined administration of PDE4 or PDE3/4 inhibitors and leukotriene receptor antagonists for the treatment of respiratory tract disorders.
    Type: Application
    Filed: September 17, 2002
    Publication date: January 20, 2005
    Inventors: Rolf Beume, Daniela Bundschuh, Christian Weimar, Stefan-Lutz Wollin
  • Tryptase inhibitors
    Patent number: 6613769
    Abstract: The invention relates to bifunctional tryptase inhibitors of formula (I) wherein H1 and H2 comprise a Q group and L is a linker of formula and the conformation of the H1, H2 and L groups is such that the groups are separated by a distance of from 20 to 45 Å. Pharmaceutical compositions and crystal forms of the compounds are described in addition to methods for producing and identifying such compounds, as well as the use of such compounds in methods of treating allergic and inflammatory diseases.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: September 2, 2003
    Assignees: Max-Planck-Gesellschaft zur Föderung der Wissenschaften. e.V., Altana Pharma AG
    Inventors: Wolfram Bode, Luis Moroder, Pedro Jose Barbosa Pereira, Andreas Bergner, Robert Huber, Christian Sommerhoff, Norbert Schaschke, Thomas Bär, Thomas Martin, Josef Stadlwieser, Wolf-Rüdiger Ulrich, Andreas Dominik, Ulrich Thibaut, Daniela Bundschuh, Rolf Beume, Karl-Josef Goebel
  • Tryptase inhibitors
    Patent number: 6489327
    Abstract: The invention relates to novel inhibitors of human tryptase which are used in the pharmaceutical industry for the production of medicaments.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 3, 2002
    Assignees: Max-Planck-Gesellschaft zur Fordrungder Wisenschaften, e.V., Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Thomas Bär, Thomas Martin, Josef Stadlwieser, Wolf-Rüdiger Ulrich, Andreas Dominik, Ulrich Thibaut, Daniela Bundschuh, Rolf Beume, Karl-Josef Goebel, Wolfram Bode, Luis Moroder, Pedro Jose Barbosa Pereira, Andreas Bergner, Robert Huber, Christian Sommerhoff, Norbert Schaschke