Patents by Inventor Rolf D. Issels

Rolf D. Issels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020127718
    Abstract: This invention is directed to ex vivo and in vivo methods for inducing the TNF-&agr; free differentiation of immature dendritic cells into mature dendritic cells as well as methods for generating said mature dendritic cells. The invention is further directed to mature dendritic cells obtainable by said methods. Furthermore, the invention is directed to therapeutic compositions comprising an effective amount of heat shock proteins of the hsp70 family or of said mature dendritic cells as well as their use in the immunotherapy of neoplastic diseases. Finally, the present invention is directed to an immunotherapy for treating neoplastic diseases in an animal.
    Type: Application
    Filed: November 7, 2001
    Publication date: September 12, 2002
    Inventors: Maria Kuppner, Rolf D. Issels, Robert Gastpar