Patents by Inventor Rolf G. Tschudin

Rolf G. Tschudin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Resonant structure for spatial and spectral-spatial imaging of free radical spin probes using radiofrequency time domain electron paramagnetic resonance spectroscopy
    Patent number: 6573720
    Abstract: A radiofrequency (RF) coil design, suitable for detecting time domain electron paramagnetic resonance (EPR) responses from spin probes after pulsed excitation using radiofrequency irradiation (60-400 MHz), is configured in an array of numerous surface coils of appropriate diameters connected in a parallel or axial configuration with appropriate spacing between individual surface coils to form a volume type resonator.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: June 3, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Nallathamby Devasahayam, James B. Mitchell, Angelo Russo, John Cook, Mobae Afeworki, Rolf G. Tschudin, Sankaran Subramanian, Ramachandran Murugesan, Frank S. Harrington, Murali K. Cherukuri
  • In vivo imaging and oxymetry by pulsed radiofrequency paramagnetic resonance
    Patent number: 5865746
    Abstract: A system for performing pulsed RF FT EPR spectroscopy and imaging includes an ultra-fast excitation subsystem and an ultra-fast data acquisition subsystem. Additionally, method for measuring and imaging in vivo oxygen and free radicals or for performing RF FT EPR spectroscopy utilizes short RF excitations pulses and ultra-fast sampling, digitizing, and summing steps.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: February 2, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Ramachandran Murugesan, Murali K. Cherukuri, James B. Mitchell, Sankaran Subramanian, Rolf G. Tschudin
  • System and method for performing in vivo imaging and oxymetry and FT microscopy by pulsed radiofrequency electron paramagnetic resonance
    Patent number: 5678548
    Abstract: A system for performing pulsed RF FT EPR spectroscopy and imaging includes an ultra-fast excitation subsystem and an ultra-fast data acquisition subsystem. Additionally, method for measuring and imaging in vivo oxygen and free radicals or for performing RF FT EPR spectroscopy utilizes short RF excitations pulses and ultra-fast sampling, digitizing, and summing steps.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: October 21, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Ramachandran Murugesan, Murali K. Cherukuri, James B. Mitchell, Sankaran Subramanian, Rolf G. Tschudin
  • Pulsed low frequency EPR spectrometer and imager
    Patent number: 5502386
    Abstract: An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.
    Type: Grant
    Filed: November 15, 1994
    Date of Patent: March 26, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: John Bourg, James Mitchell, Mark Mirotznik, Bradley Roth, Sankaran Subramanian, Murali Cherukuri, Paul G. Zablocky, Thomas J. Pohida, Paul D. Smith, Walter S. Friauf, Rolf G. Tschudin