Patents by Inventor Rolf Geiger

Rolf Geiger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4053588
    Abstract: Pharmaceutical preparations containing an L-pyroglutamic acid amide, processes for their preparation and methods of treating psychotic diseases with them.
    Type: Grant
    Filed: May 12, 1975
    Date of Patent: October 11, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Hans Wissmann, Hansjorg Kruse, Michel Peterfalvi
  • Patent number: 4024248
    Abstract: The present invention relates to peptides having strong LH-RH/FSH-RH activity, wherein Gly in the 6-position is replaced by different substituted amino acids and in the 10-position there is glycinamide or glycine in the 10-position is replaced by a NH-alkyl group with 1-3 carbon atoms or a NH-cyclopropyl group. The invention relates as well to a process for manufacturing said peptides, and to pharmaceutical preparations containing said peptides.
    Type: Grant
    Filed: August 7, 1975
    Date of Patent: May 17, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Jurgen Kurt Sandow
  • Patent number: 4014861
    Abstract: A process for manufacture of insulin, analogs and derivatives thereof by treating an insulin compound wherein the A- and B-chains are linked by a bis-methionyl-carbonyl-bridge, with cyano bromide.
    Type: Grant
    Filed: June 10, 1975
    Date of Patent: March 29, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rolf Geiger, Rainer Obermeier
  • Patent number: 4013791
    Abstract: Novel peptide derivatives and a method of preparing the same are described. These compounds are useful in the diagnosis and treatment of hypertension.
    Type: Grant
    Filed: December 3, 1975
    Date of Patent: March 22, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Rolf Geiger, Ernst Lindner, Bernward Scholkens
  • Patent number: 4013628
    Abstract: A process for the manufacture of insulin and derivatives thereof by treating an insulin derivative, wherein the A-chain is cross-linked with the B-chain by means of a sulfonyl diethyl-bisoxycarbonyl bridge and the B-chain may contain an acyl group in the 1-position, with alkali metal hydroxides or quaternary organic bases having a pH value of more than 13.
    Type: Grant
    Filed: August 14, 1975
    Date of Patent: March 22, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rainer Obermeier, Rolf Geiger
  • Patent number: 4003884
    Abstract: Peptides having LH-RH/FSH-RH activity useful for treatment of male and female sterility.
    Type: Grant
    Filed: May 16, 1975
    Date of Patent: January 18, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Jurgen K. Sandow
  • Patent number: 3937820
    Abstract: A novel insulin composition of improved stability and compatibility comprising in an aqueous suspension crystallized insulin and amorphous des-phenyl-alanine.sup.B1 insulin of the same species, and a method for its manufacture.
    Type: Grant
    Filed: November 14, 1973
    Date of Patent: February 10, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Adolf Mager, Hans-Hermann Schone, Rolf Geiger, Franz Enzmann
  • Patent number: 3931139
    Abstract: The invention relates to tripeptide amides containing pyroglutamine, proline and histidine as amino acids having anti-depressive activity and a process for their manufacture.
    Type: Grant
    Filed: August 22, 1974
    Date of Patent: January 6, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Rolf Geiger, Wolfgang Konig, Hansjorg Kruse, Karl Seeger
  • Patent number: 3931141
    Abstract: Heptapeptides of the general formulaHOOC--(CH.sub.2).sub.3 --CO--Ala--Tyr--Gly--Trp--X--Asp--Phe--NH.sub.2in which X represents leucine or methionine, and process for preparing them by reacting tert.butyl-protected heptapeptides with glutaric acid anhydride and subsequently splitting off the protective groups with the aid of trifluoroacetic acid.
    Type: Grant
    Filed: November 15, 1973
    Date of Patent: January 6, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Wissmann, Rolf Geiger, Rudolf Schleyerbach