Patents by Inventor Rolf Guller

Rolf Guller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6709584
    Abstract: A device for analyzing substances by thin layer chromatography comprises a solvent trough with two solvent channels, wherein two wall plates are mounted in the solvent trough, enabling thin layer plates to be arranged obliquely with respect to the horizontal in the solvent channels. The substance to be analyzed can thus be dropped or applied onto the thin layer plates from above, and solvent can be supplied to the solvent channels from above at a solvent supply point. The upward migration of components of the substance to be analyzed can thus be started without changing the position of the thin layer plate for this purpose.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: March 23, 2004
    Assignee: Chemspeed Ltd.
    Inventors: Rolf Güller, Séraphin Munch, Philippe Jablonski, Josef Schröer
  • Patent number: 6605256
    Abstract: A device for carrying out a multiplicity of chemical, biochemical or physical processes in parallel has a plurality of switching blocks (1), to which a multiplicity of reaction vessels (5) are removably fastened. Liquids, gases and/or solids can be supplied to and/or extracted from the reaction vessels (5) through the switching blocks (1). Each switching block (1) comprises a gas duct plate (11) and a functional plate (12) which is arranged so that it can be displaced on it. The gas duct plate (11) has a multiplicity of through-holes, a gas duct and a multiplicity of gas duct holes extending from the gas duct to the functional plate (12) and the functional plate (12) has a multiplicity of through-holes and depressions open to the gas duct plate (11). Depending on the position of the plates, through-holes, depressions or sealing surfaces of the functional plate (12) are located opposite to through-holes and gas duct holes of the gas duct plate (11).
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: August 12, 2003
    Assignee: Chemspeed, Ltd.
    Inventors: Rolf Güller, Séraphin Munch, Thomas Gees, Hansjörg Tschirky
  • Patent number: 6558632
    Abstract: An apparatus for providing temperature control and agitation to a plurality of reaction vessels comprises a plurality of elastic receptacles on a block, each receptacle supporting a reaction vessel below its neck, and, a plurality of elastic couplings, each coupling retaining a reaction vessel at its neck section. A flow channel is provided within the block to transfer a liquid temperature control medium to the reaction vessels. The flow channel is routed to each receptacle individually, thereby supplying the medium directly to the corresponding reaction vessel. A shaking arrangement is provided to agitate the reaction vessels by moving the receptacles horizontally relative to the couplings. The greatest deflection of each reaction vessel occurs at its base, while the neck sections are subjected to slight movement.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: May 6, 2003
    Assignee: Chemspeed Ltd.
    Inventors: Rolf Güller, Séraphin Munch, Philippe Jablonski, Hansjörg Tschirky
  • Publication number: 20030013187
    Abstract: A device according to the invention for analyzing substances by means of thin layer chromatography comprises a solvent trough (1) with two solvent channels (11, 12). Two wall plates (4, 5) are mounted in the solvent trough (1), enabling thin layer plates (2, 3) to be arranged standing obliquely with respect to the horizontal in the solvent channels (11, 12). The substance to be analyzed can thus be dropped or applied onto the thin layer plates (2, 3) from above, and solvent can be supplied to the solvent channels (11, 12) from above at a solvent supply point (111, 121). The upward migration of components of the substance to be analyzed can thus be started without the position of the thin layer plate (2, 3) needing to be changed for this purpose.
    Type: Application
    Filed: July 30, 2002
    Publication date: January 16, 2003
    Inventors: Rolf Guller, Seraphin Munch, Philippe Jablonski, Josef Schroer
  • Patent number: 6268499
    Abstract: The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof comprisingepoxidation of a compound of formula 2 or a salt thereof wherein A, R1 and R2 are as herein defined. These compounds are useful in the synthesis of renin inhibitors.
    Type: Grant
    Filed: July 13, 1999
    Date of Patent: July 31, 2001
    Assignee: Hoffman-La Roche Inc.
    Inventors: Rolf Güller, Bruno Lohri, Rudolf Schmid
  • Patent number: 6150526
    Abstract: Piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the piperidine derivatives of general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Z, m and n are as described herein.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: November 21, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alfred Binggeli, Volker Breu, Daniel Bur, Walter Fischli, Rolf Guller, Georges Hirth, Hans-Peter Marki, Marcel Muller, Christian Oefner, Heinz Stadler, Eric Vieira, Maurice Wilhelm, Wolfgang Wostl
  • Patent number: 6051712
    Abstract: Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Z, m and n are as described herein.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: April 18, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alfred Binggeli, Volker Breu, Daniel Bur, Walter Fischli, Rolf Guller, Georges Hirth, Hans-Peter Marki, Marcel Muller, Christian Oefner, Heinz Stadler, Eric Vieira, Maurice Wilhelm, Wolfgang Wostl