Patents by Inventor Rolf Hermann Heinrich Madaus

Rolf Hermann Heinrich Madaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyhydroxyphenylchromanone salts and therapeutic composition
    Patent number: 4061765
    Abstract: Salts of polyhydroxyphenylchromanones, e.g., silymarin or one or more members of the silymarin group, are reacted with a monoaminopolyhydroxy alcohol of the formula ##STR1## wherein X IS AN INTEGER FROM 3 TO 5; ANDR.sub.1 and R.sub.2 are hydrogen, lower alkyl or hydroxyalkylTo give chemotherapeutic salt compounds which are water soluble while retaining a high degree of medical effectiveness. The salt compounds can be administered to mammals to antagonize or mitigate liver damage and inflammation.
    Type: Grant
    Filed: July 29, 1976
    Date of Patent: December 6, 1977
    Assignee: Dr. Madaus & Co.
    Inventors: Rolf Hermann Heinrich Madaus, Gunter Halbach, Wilfried Trost
  • Process for the preparation of antacid aluminum hydroxycarbonate hydrate
    Patent number: 4053568
    Abstract: A basic aluminum hydroxycarbonate hydrate, usable as an antacid, is prepared by simultaneously adding aqueous solutions of aluminum sulfate and alkali hydrogen carbonate or alkali carbonate to water while maintaining a neutral or weakly alkaline pH and adjusting the pH-value of the reaction mixture, after completed precipitation, to about 6.0 by adding an aluminum salt of a strong acid.
    Type: Grant
    Filed: March 28, 1975
    Date of Patent: October 11, 1977
    Assignee: Dr. Madaus & Co.
    Inventors: Rolf Hermann Heinrich Madaus, Klaus Gorler
  • Silybin polymers and therapeutic compositions
    Patent number: 3997671
    Abstract: New, highly effective therapeutic polymers of oligomers of Silybin are provided as well as a process for making same employing organic solvent/mineral acid systems in which Silybin auto-condenses to oligomers thereof having polymerization numbers of, e.g., 2 to 8.
    Type: Grant
    Filed: April 4, 1975
    Date of Patent: December 14, 1976
    Assignee: Dr. Madaus & Co.
    Inventors: Rolf Hermann Heinrich Madaus, Gunter Halbach, Wilfried Trost
  • Salt of the silymarin group with aminopolyhydroxy alcohols
    Patent number: 3994925
    Abstract: Salts of polyhydroxyphenylchromanones, e.g., silymarin or one or more members of the silymarin group, are reacted with a monoaminopolyhydroxy alcohol of the formula ##EQU1## wherein X IS AN INTEGER FROM 3 TO 5; ANDR.sub.1 and R.sub.2 are hydrogen, lower alkyl or hydroxyalkylTo give chemotherapeutic salt compounds which are water soluble while retaining a high degree of medical effectiveness. The salt compounds can be administered to mammals to antagonize or mitigate liver damage and inflammation.
    Type: Grant
    Filed: January 21, 1974
    Date of Patent: November 30, 1976
    Assignee: Dr. Madaus & Co.
    Inventors: Rolf Hermann Heinrich Madaus, Gunter Halbach, Wilfried Trost