Patents by Inventor Rolf Herter

Rolf Herter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4957920
    Abstract: New benzimidazoles corresponding to the general formula I ##STR1## are described, in which the pyridazinone ring is attached in the 5- or 6- position of the benzimidazole ring and R.sup.1 denotes a hydrogen atom or a straight chained or branched C.sub.1 to C.sub.4 alkyl group, R.sup.2 denotes a hydrogen atom, a straight chained or branched C.sub.1 to C.sub.4 alkyl group, a C.sub.1 to C.sub.4 alkoxy group, a hydroxy group, a halogen atom, an amino group or a nitro group, A denotes a hydrogen atom, a group of the formula ##STR2## wherein R.sup.3 denotes a hydrogen atom, an optionally substituted C.sub.1 to C.sub.4 alkyl group or a C.sub.1 to C.sub.4 alkoxy group and B denotes a cyano group, a benzoyl group or a phenylsulphonyl group, or A denotes a group of the formula ##STR3## in which m has the value of 2 or 3 and n represents an integer from 1 to 6, and the physiologically acceptable salts thereof as well as processes for their preparation and pharmaceutical preparations containing these compounds.
    Type: Grant
    Filed: March 15, 1988
    Date of Patent: September 18, 1990
    Assignee: Heumann Pharma GmbH & Co.
    Inventors: Peter Morsdorf, Helmut Schickaneder, Rolf Herter, Volker Pfahlert, Heidrun Engler, Kurt H. Ahrens
  • Patent number: 4954501
    Abstract: New 6-phenyldihydro-3(2H)-pyridazinones corresponding to the following general formula ##STR1## are described. These compounds are readily prepared in a form suitable for oral administration and are distinguished by a high positive inotropic action and have only a slight effect on blood pressure and cardiac frequency. A process for their preparation and pharmaceutical preparations containing these compounds are also described.
    Type: Grant
    Filed: September 21, 1988
    Date of Patent: September 4, 1990
    Assignee: Heumann Pharma GmbH & Co.
    Inventors: Rolf Herter, Peter Morsdorf, Volker Pfahlert, Heidrun Engler, Helmut Schickaneder, Kurt-Henning Ahrens
  • Patent number: 4833141
    Abstract: The invention relates to new 1,4-piperazine compounds corresponding to the following general formula ##STR1## which show improved antimycotic activity in relation to the known compounds miconazol and ketoconazol.
    Type: Grant
    Filed: July 2, 1987
    Date of Patent: May 23, 1989
    Assignee: Heumann Pharma GmbH & Co.
    Inventors: Helmut Schickaneder, Rolf Herter, Hartmut Vergin, Heidrun Engler, Kurt H. Ahrens
  • Patent number: 4830586
    Abstract: An improved double acting diaphragm pump utilizes at least one supplemental diaphragm and associated pressure chamber arranged coaxially with the connecting shaft of the main diaphragms. The supplemental chambers are connected via parallel pressure lines or conduits to the pressure source for the main diaphragms and associated pressure chambers.
    Type: Grant
    Filed: December 21, 1987
    Date of Patent: May 16, 1989
    Assignee: The ARO Corporation
    Inventors: Rolf Herter, C. Bernard Sartran, Arno Grabowski
  • Patent number: 4738960
    Abstract: 1,3,4-Thiadiazole derivatives corresponding to the general formula I ##STR1## which constitute highly effective inhibitors for histamine-H.sub.2 receptors are described. These compounds in addition have a cytoprotective action.
    Type: Grant
    Filed: November 19, 1985
    Date of Patent: April 19, 1988
    Assignee: Ludwig Heumann & Co. GmbH
    Inventors: Helmut Schickaneder, Rolf Herter, Kurt Wegner, Walter Schunack, Istvan Szelenyi, Stefan Postius, Kurt H. Ahrens
  • Patent number: 4666921
    Abstract: Special pyrazole derivatives corresponding to the general formula I which have a highly selective action on histamine-H.sub.2 receptors are described. Compared with other drugs known to be effective in their action on histamine-H.sub.2 receptors, these compounds have improved pharmacological properties. A method of preparation of these compounds is also described.
    Type: Grant
    Filed: October 15, 1985
    Date of Patent: May 19, 1987
    Assignee: Ludwig Heumann & Co. GmbH
    Inventors: Rolf Herter, Helmut Schickaneder, Peter Morsdorf, Stefan Postius, Istvan Szelenyi, Kurt H. Ahrens
  • Patent number: 4659721
    Abstract: Alkanol derivatives corresponding to the general formula IR.sup.1 R.sup.2 N--(CH.sub.2).sub.m --Q--CH.sub.2 X--CH.sub.2 --Y--(CH.sub.2).sub.n --NHR.sup.3 (I)which have a highly selective action on histamine-H.sub.2 receptors are described. Due to this action, these compounds may advantageously be used for treatment of diseases caused by raised gastric secretion.
    Type: Grant
    Filed: January 22, 1985
    Date of Patent: April 21, 1987
    Assignee: Ludwig Heumann & Co. GmbH
    Inventors: Helmut Schickaneder, Stefan Postius, Istvan Szelenyi, Peter Morsdorf, Rolf Herter, Kurt H. Ahrens
  • Patent number: 4656180
    Abstract: Diamine derivatives corresponding to the general formula IR.sup.1 R.sup.2 N--(CH.sub.2).sub.m --Q--A--NH--R--NH--B--Q'--(CH.sub.2).sub.n NR.sup.3 R.sup.4 (I)which have a highly selective action on histamine-H.sub.2 receptors and are therefore suitable for use as anti-ulcerative agents are described. Processes for the preparation of these compounds and pharmaceutical preparations containing these compounds are also described.
    Type: Grant
    Filed: March 5, 1985
    Date of Patent: April 7, 1987
    Assignee: Ludwig Heumann & Co., GmbH
    Inventors: Stefan Postius, Rolf Herter, Peter Morsdorf, Helmut Schickaneder, Istvan Szelenyi, Kurt H. Ahrens
  • Patent number: 4599346
    Abstract: The invention relates to new propan-2-ol derivatives corresponding to the following general formula ##STR1## in which R represents ##STR2## and to salts thereof with pharmacologically acceptable acids. These compounds have a selective effect on histamine-H.sub.2 -receptors.
    Type: Grant
    Filed: July 16, 1984
    Date of Patent: July 8, 1986
    Assignee: Ludwig Heumann & Co., GmbH
    Inventors: Helmut Schickaneder, Stefan Postius, Rolf Herter, Peter Morsdorf, Istvan Szelenyi, Kurt H. Ahrens
  • Patent number: 4559344
    Abstract: The invention relates to new pyridine-pyrimidinone derivatives corresponding to the following general formula ##STR1## wherein R.sup.1 represents linear C.sub.1-6 alkyl or cycloalkyl and R.sup.2 represents linear C.sub.1-6 alkyl or R.sup.1 and R.sup.2 together with the nitrogen atom form a pyrrolidine or piperidine ring;Alk represents a linear alkylene chain C.sub.1-6 ;Q represents a benzene ring, furan ring, thiophene ring or thiazole ring;X represents oxygen, Y is a single bond and m is 2, 3 or 4 when Q represents benzene;X represents methylene, Y represents sulfur and m is 2 or 3 when Q is furan, thiophene or thiazole; andR.sup.3 represents a hydrogen atom or a lower alkyl group.These compounds show improved H.sub.2 -antagonistic activity.
    Type: Grant
    Filed: January 26, 1984
    Date of Patent: December 17, 1985
    Assignee: Ludwig Heumann & Co. GmbH
    Inventors: Helmut Schickaneder, Peter Morsdorf, Stefan Postius, Istvan Szelenyi, Rolf Herter, Herbert Hansen, Kurt H. Ahrens