Patents by Inventor Rolf Hofer

Rolf Hofer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8034395
    Abstract: The invention relates to a method for precipitating mono or multiple layers of a mixture of organophosphoric acids of the general formula I (A) Y—B—OPO3H2 ??(IA) or of organophosphonic acids of the general formula I (B) Y—B—PO3H2 ??(IB) and the salts thereof, wherein Y and B are defined in the specification. According to the invention, precipitation occurs on substrate surfaces of pure or mixed oxides, nitrides or carbides of metals and semiconductors, in particular as surfaces of sensor platforms, implants and medical accessory devices. The invention also relates to the use thereof as part of coated sensor platforms, implants and medical accessory devices.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: October 11, 2011
    Assignee: Bayer Technology Services GmbH
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schürmann-Mader, Markus Ehrat, Samuele Tosatti
  • Publication number: 20100280601
    Abstract: The invention relates to a method for precipitating mono or multiple layers of a mixture of organophosphoric acids of the general formula I (A) Y—B—OPO3H2 ??(IA) or of organophosphonic acids of the general formula I (B) Y—B—PO3H2 ??(IB) and the salts thereof, wherein Y and B are defined in the specification. According to the invention, precipitation occurs on substrate surfaces of pure or mixed oxides, nitrides or carbides of metals and semiconductors, in particular as surfaces of sensor platforms, implants and medical accessory devices. The invention also relates to the use thereof as part of coated sensor platforms, implants and medical accessory devices.
    Type: Application
    Filed: May 12, 2010
    Publication date: November 4, 2010
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schürmann-Mader, Markus Ehrat, Samuele Tosatti
  • Patent number: 7740896
    Abstract: The invention relates to a method for precipitating mono or multiple layers of organophosphoric acids of the general formula I (A) Y—B—OPO3H2??(IA) or of organophosphonic acids of the general formula I (B) Y—B—PO3H2??(IB) and the salts thereof, wherein B is an alkyl, alkenyl, alkinyl, aryl, aralkyl, hetaryl or hetarylalkyl residue and Y is hydrogen or a functional group from the hydroxy, carboxy, amino, optionally low-alkyl-substituted mono or dialkylamino series, thiol, or a negative acid group from the ester, phosphate, phosphonate, sulfate, sulfonate, maleimide, succinimydyl, epoxy, acrylate series, wherein a biological, biochemical or synthetic indicator element may be coupled to B or Y by addition or substitution reaction, wherein compounds may also be added conferring the substrate surface a resistance to protein adsorption and/or to cell adhesion and in the B chain may optionally be comprised one or more ethylene oxide groups, rather than one or more —CH2— groups.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: June 22, 2010
    Assignee: Bayer Technology Services GmbH
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schürmann-Mader, Markus Ehrat, Samuele Tosatti
  • Patent number: 7517546
    Abstract: The invention relates to a method for precipitating mono or multiple layers of organophosphoric acids of the general formula I (A) Y—B—OPO3H2??(IA) or of organophosphonic acids of the general formula I (B) Y—B—PO3H2??(IB) and the salts thereof, wherein B is an alkyl, alkenyl, alkinyl, aryl, aralkyl, hetaryl or hetarylalkyl residue and Y is hydrogen or a functional group from the hydroxy, carboxy, amino, optionally low-alkyl-substituted mono or dialkylamino series, thiol, or a negative acid group from the ester, phosphate, phosphonate, sulfate, sulfonate, maleimide, succinimydyl, epoxy, acrylate series, wherein a biological, biochemical or synthetic indicator element may be coupled to B or Y by addition or substitution reaction, wherein compounds may also be added conferring the substrate surface a resistance to protein adsorption and/or to cell adhesion and in the B chain may optionally be comprised one or more ethylene oxide groups, rather than one or more —CH2- groups.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: April 14, 2009
    Assignee: Bayer Technology Services GmbH
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schürmann-Mader, Markus Ehrat, Samuele Tosatti
  • Publication number: 20090061506
    Abstract: The invention relates to a method for precipitating mono or multiple layers of organophosphoric acids of the general formula I (A) Y—B—OPO3H2??(IA) or of organophosphonic acids of the general formula I (B) Y—B—PO3H2??(IB) and the salts thereof, wherein B is an alkyl, alkenyl, alkinyl, aryl, aralkyl, hetaryl or hetarylalkyl residue and Y is hydrogen or a functional group from the hydroxy, carboxy, amino, optionally low-alkyl-substituted mono or dialkylamino series, thiol, or a negative acid group from the ester, phosphate, phosphonate, sulfate, sulfonate, maleimide, succinimydyl, epoxy, acrylate series, wherein a biological, biochemical or synthetic indicator element may be coupled to B or Y by addition or substitution reaction, wherein compounds may also be added conferring the substrate surface a resistance to protein adsorption and/or to cell adhesion and in the B chain may optionally be comprised one or more ethylene oxide groups, rather than one or more —CH2- groups.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 5, 2009
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schurmann-Mader, Markus Ehrat, Samuele Tosatti
  • Patent number: 6884628
    Abstract: Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non-specific interaction, adsorption or attachment of molecular or ionic components present in an analyte solution. Chemical, biochemical or biological groups that are able to recognize, interact with and bind specifically to target molecules in the material containing the analyte to be detected can be coupled to, integrated into, or absorbed to the multifunctional copolymers. These multifunctional copolymer coatings are compatible with a variety of different established methods to detect, sense and quantify the target molecule in an analyte.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: April 26, 2005
    Assignees: Eidgenossische Technische Hochschule Zurich, Universitat Zurich
    Inventors: Jeffrey A. Hubbell, Marcus Textor, Donald L. Elbert, Stephanie Finken, Rolf Hofer, Nicholas D. Spencer, Laurence Ruiz-Taylor
  • Publication number: 20040253596
    Abstract: The invention relates to a recognition surface on a carrier with an (in relation to the surface) optimal binding capacity for recognizing and binding one or more analytes from one or more samples brought into contact with this surface, wherein
    Type: Application
    Filed: February 27, 2004
    Publication date: December 16, 2004
    Inventors: Michael Pawlak, Gert Ludwig Duveneck, Ning-Ping Huang, Susan Margaret De Paul, Marcus Textor, Rolf Hofer, Eveline Schurmann-Mader
  • Publication number: 20030186914
    Abstract: The invention relates to a method for precipitating mono or multiple layers of organophosphoric acids of the general formula I (A)
    Type: Application
    Filed: March 5, 2003
    Publication date: October 2, 2003
    Inventors: Rolf Hofer, Michael Pawlak, Marcus Textor, Eveline Schurmann-Mader, Markus Ehrat, Samuele Tosatti
  • Publication number: 20020128234
    Abstract: Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non-specific interaction, adsorption or attachment of molecular or ionic components present in an analyte solution. Chemical, biochemical or biological groups can be coupled to, integrated into or absorbed to the multifunctional polymer that are able to recognize, interact with and bind specifically to target molecules in the material containing the analyte to be detected. These multifunctional polymer coatings are compatible with a variety of different established methods to detect, sense and quantify the target molecule in an analyte.
    Type: Application
    Filed: April 28, 2000
    Publication date: September 12, 2002
    Inventors: Jeffrey A. Hubbell, Marcus Textor, Donald L. Elbert, Stephanie Finken, Rolf Hofer, Nicholas D. Spencer, Laurence Ruiz-Taylor
  • Patent number: 5698660
    Abstract: A copolyamide with an improved modulus of elasticity for the melt-spinning of filaments consists of at least 75 wt. % of a linear polyamide base polymer with a melting point of 150.degree.-320.degree. C. and at least 0.5 wt. % of a block comonomer which is incorporated into the base polymer and has a glass transition temperature (T.sub.g) between 130.degree. and 330.degree. C. and a degree of polymerization (DP) of <100. The filaments produced from the modified copolymer with an initial modulus of 500 to 1500 cN/tex are suitable for use in the production of technical fabrics.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: December 16, 1997
    Assignee: Rhone-Poulenc Viscosuisse SA
    Inventors: Roland Stahlin, Rolf Hofer, Jean Coquard