Patents by Inventor Rolf Krattenmacher

Rolf Krattenmacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030203902
    Abstract: This invention describes the new, nonsteroidal gestagens of general formula I 1
    Type: Application
    Filed: February 5, 2003
    Publication date: October 30, 2003
    Applicant: SCHERING AKTIENGESELLSCHAFT
    Inventors: Manfred Lehmann, Klaus Schoellkopf, Peter Strehlke, Nikolaus Heinrich, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 6548534
    Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar1, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: April 15, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Manfred Lehmann, Klaus Schoellkopf, Peter Strehlke, Nikolaus Heinrich, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Publication number: 20020016365
    Abstract: This invention describes the new, nonsteroidal gestagens of general formula I 1
    Type: Application
    Filed: July 27, 2001
    Publication date: February 7, 2002
    Applicant: SCHERING AKTIENGESELLSCHAFT
    Inventors: Manfred Lehmann, Klaus Schoellkopf, Peter Strehlke, Karl-Heinrich Fritzemeier, Nikolaus Heinrich, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 6344454
    Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: February 5, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Manfred Lehmann, Klaus Schoellkopf, Peter Strehlke, Nikolaus Heinrich, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 6245804
    Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: June 12, 2001
    Assignee: Schering Aktiengesellschaft
    Inventors: Manfred Lehmann, Klaus Schoellkopf, Peter Strehlke, Nikolaus Heinrich, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 6147065
    Abstract: Described are 14,17-C.sub.2 -bridged steroids of the formula (I) defined in the specification. The compounds are available, even after peroral administration, with high gestagenic action and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: July 28, 1999
    Date of Patent: November 14, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Schollkopf, Wolfgang Halfbrodt, Joachim Kuhnke, Wolfgang Schwede, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 5973172
    Abstract: The invention describes 14,17-C.sub.2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are in contrast, with the disclaimed compound, the new compounds are available even after peroral administration with high gestagenic action and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: October 26, 1999
    Assignee: Schering Akitengesellschaft
    Inventors: Klaus Schollkopf, Wolfgang Halfbrodt, Joachim Kuhnke, Wolfgang Schwede, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 5827842
    Abstract: The invention describes 14,17-C.sub.2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are, in contrast with the disclaimed compound 14,17-ethano-19-norpregn-4-ene-3,20-dione bioavailable even after peroral administration with high gestagenic action and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: December 26, 1995
    Date of Patent: October 27, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Schollkopf, Wolfgang Halfbrodt, Joachim Kuhnke, Wolfgang Schwede, Karl-Heinrich Fritzemeier, Rolf Krattenmacher, Hans-Peter Muhn
  • Patent number: 5703066
    Abstract: In this invention, the new etheno- and ethano-19,11-bridged 4-estrenes of general formula I ##STR1## are described, in whichW, R.sup.1, R.sup.2, R.sup.6a, R.sup.6b, R.sup.7, R.sup.14, R.sup.15, R.sup.16, R.sup.11, R.sup.11' and R.sup.19 have the meaning indicated in the description, as well as a process for their production.The new compounds have strong progestational activity and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 30, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Eckhard Ottow, Wolfgang Schwede, Wolfgang Halfbrodt, Karl-Heinrich Fritzemeier, Rolf Krattenmacher
  • Patent number: 5523298
    Abstract: In this invention, the new etheno- and ethano-19,11-bridged 4-estrenes of general formula I ##STR1## are described, in which W, R.sup.1, R.sup.2, R.sup.6a, R.sup.6b, R.sup.7, R.sup.14, R.sup.15, R.sup.16, R.sup.11, R.sup.11' and R.sup.19 have the meaning indicated in the description, as well as a process for their production.The new compounds have strong progestational activity and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: June 4, 1996
    Assignee: Schering Aktiengesellschaft
    Inventors: Eckhard Ottow, Wolfgang Schwede, Wolfgang Halfbrodt, Karl-Heinrich Fritzemeier, Rolf Krattenmacher
  • Patent number: 5491137
    Abstract: 14.alpha.,17.alpha.-(Propano-and 17.sup.2 -propeno)-estratrienes of general formula I ##STR1## in which R.sup.1 means a hydrogen atom, a methyl or an acyl group with 1-12 carbon atoms,R.sup.2 means a hydrogen atom or an acyl group with 1-12 carbon atoms and ##STR2## a C--C single or double bond. The new compounds of general formula I are estrogen effective just as ethinyl estradiol.
    Type: Grant
    Filed: October 29, 1993
    Date of Patent: February 13, 1996
    Assignee: Schering Aktiengesellschaft
    Inventors: James R. Bull, Walter Elger, Karl-Heinrich Fritzemeier, Rolf Krattenmacher
  • Patent number: 5439902
    Abstract: The new 14.alpha.,16.alpha.-ethano- and 14.alpha.,16.alpha.-etheno-estratrienes of general formula I, ##STR1## are described, in which A-B means a C-C single bond or C-C double bond,R.sub.1 means a hydrogen atom, a methyl or acyl group with 1-12 carbon atoms andX means oxygen or ##STR2## in which R.sub.2 represents a hydrogen atom or an acyl group with 1-12 carbon atoms,and a process for their production. The new compounds are very strong estrogens and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: August 8, 1995
    Assignee: Schering Aktiengesellschaft
    Inventors: Henry Laurent, Peter Esperling, Walter Elger, Rolf Krattenmacher