Patents by Inventor Rolf Kretzschmar

Rolf Kretzschmar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Active compounds for use in the treatment of tumors
    Patent number: 5057304
    Abstract: Antitumor compositions and methods in which a cancerostatic agent and an effective amount of (+)-verapamil, (+)-gallopamil, (+)-devapamil and/or (+)-emopamil which reinforce the antitumor action of the cancerostatic agent are administered to a patient either together or in sequence.
    Type: Grant
    Filed: January 3, 1989
    Date of Patent: October 15, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Rolf Kretzschmar, Erich Schlick, Michel Eichelbaum
  • Anipamil for the treatment of chronic renal failure
    Patent number: 5039709
    Abstract: The use of anipamil and its salts with physiologically tolerated acids for the treatment of chronic renal failure is described.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: August 13, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans D. Lehmann, Rolf Kretzschmar, Laurence Chan, Robert W. Schrier
  • Novel pyridazinone-imines and their physiologically tolerated addition salts with acids, their preparation and therapeutic agents containing these compounds
    Patent number: 4820821
    Abstract: Novel 1-phenyl-4(1H)-pyridazinone-imines of the formula (I) ##STR1## which are substituted at the imine nitrogen, and their addition salts with a physiologically tolerated acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs, in particular as antidepressants, antiparkinson drugs and antihypotonic agents.
    Type: Grant
    Filed: April 17, 1987
    Date of Patent: April 11, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Rudolf Kropp, Marco Thyes, Rainer Schlecker, Albrecht Franke, Franz Reicheneder, Dora I. Reicheneder, August Amann, Hans-Juergen Teschendorf, Rolf Kretzschmar, Martin Traut, Josef Gries
  • Combination preparation
    Patent number: 4798811
    Abstract: A combination of verapamil, gallopamil or anipamil and acetylsalicylic acid in a weight ratio of from 10:1 to 2:1 being useful in the treatment of circulatory disorders.
    Type: Grant
    Filed: January 7, 1988
    Date of Patent: January 17, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans D. Lehmann, Rolf Kretzschmar, Klaus-Juergen Hahn
  • .OMEGA.-Cyano-1, .OMEGA.-diphenyl-azaalkane derivatives, their preparation and drugs containing them
    Patent number: 4438131
    Abstract: .omega.-Cyano-1,.omega.-diphenyl-azaalkane derivatives of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, m and n have the meanings given in the description, and salts thereof with physiologically tolerated acids, are useful in treating cardiovascular disorders.
    Type: Grant
    Filed: March 30, 1982
    Date of Patent: March 20, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Oskar Ehrmann, Manfred Raschack, Josef Gries, Rolf Kretzschmar, Hans D. Lehmann, Ludwig Friedrich, Dirk Wuppermann, Frank Zimmermann, Werner Seitz, Hans J. Treiber, Ferdinand Dengel, Wolfram Frank, Hans-Georg Kurbjuweit, Claus D. Mueller
  • Novel carbamates, their preparation, and pharmaceutical formulations containing these compounds
    Patent number: 4335138
    Abstract: Novel carbamates derived from substituted cyclic .beta.-keto-alcohols, their preparation, and pharmaceutical formulations which contain these compounds and which may be used as hypnotics in the treatment of sleep disturbance and as sedatives.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: June 15, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter-Wielant Wiersdorff, Karl-Heinz Geiss, Harald Weifenbach, Wolfgang Worstmann, Dieter Lenke, Rolf Kretzschmar
  • 4-(Alpha-hydroxy-isopropyl)-5-phenyl-oxazolidin-2-one
    Patent number: 4179442
    Abstract: The present invention is related to new oxazolidin-2-one derivatives having the general formula ##STR1## The invention is further related to a process for the treatment of somnipathy and tension conditions as well as epilepsy conditions in humans by administering a compound of the above general formula to a human suffering from such conditions.
    Type: Grant
    Filed: August 9, 1978
    Date of Patent: December 18, 1979
    Inventors: Friedrich-Gero Kollensperger, York Hartleben, Rolf Kretzschmar, Bernhard Neteler
  • Oxazolidinones as therapeutic agents
    Patent number: 4139538
    Abstract: The present invention is related to oxazolidin-2-one derivatives having the general formula ##STR1## The invention is further related to a process for the treatment of somnipathy and tension conditions as well as epilepsy conditions in humans by administering a compound of the above general formula to a human suffering from such conditions.
    Type: Grant
    Filed: August 30, 1976
    Date of Patent: February 13, 1979
    Assignee: Nordmark-Werke GmbH
    Inventors: Friedrich-Gero Kollensperger, York Hartleben, Rolf Kretzschmar, Bernhard Neteler
  • Anhydro-2-mercapto-1,3,4-thiadiazolium hydroxides
    Patent number: 4000147
    Abstract: New anhydro-2-mercapto-1,3,4-thiadiazolium hydroxides substituted in the 4- and 5-position, their manufacture and their use as medicaments.
    Type: Grant
    Filed: February 10, 1975
    Date of Patent: December 28, 1976
    Assignee: BASF Aktiengesellschaft
    Inventors: August Amann, Horst Koenig, Peter Thieme, Hubert Giertz, Rolf Kretzschmar