Patents by Inventor Rolf Meyer

Rolf Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12290785
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: May 6, 2025
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Patent number: 11771707
    Abstract: Embodiments of the present invention are directed to a plurality of substantially spherical microspheres comprising at least one API substantially dispersed in at least one polymer and a lyoprotectant on an outside surface of the plurality of substantially spherical microspheres, wherein the plurality of substantially spherical microspheres have a D99[num] particle diameter of less than about 10 ?m; a D90[num] circularity value of from about 0.8 to about 1.0; and comprise API in a weight of about 20 to about 40 wt. % of the polymer. Other embodiments relate to injectable compositions comprising such microspheres and methods of treating a number of conditions by administering such injectable compositions to a subject.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: October 3, 2023
    Assignee: SPINETHERA
    Inventors: Jeffrey Missling, Emily R. Rolfes Meyering, Henry Meyer, Celeste Ondich
  • Patent number: 11659993
    Abstract: The invention relates to a method for determining the occurrence of a vascular collapse of a blood vessel in or on the eye. According to the invention, it is proposed that the vascular collapse be determined from a measured temporal change of blood flow in the blood vessel.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: May 30, 2023
    Assignee: I-DYNAMOMETER GMBH
    Inventor: Rolf Meyer-Schwickerath
  • Patent number: 11529452
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: December 20, 2022
    Assignee: MINNETRONIX, INC.
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Patent number: 11147540
    Abstract: Disclosed embodiments include methods and devices for introducing a sheath into a human or animal subject. Some embodiments include a puncture tool that may simultaneously deliver a sheath and a needle to a desired anatomical location. The needle may be removed and the sheath may be used to define a space that may be used to conduct a procedure.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: October 19, 2021
    Assignee: Minnetronix, Inc.
    Inventors: Emily Rolfes Meyering, Elizabeth Scheurer, Aaron McCabe
  • Publication number: 20210186988
    Abstract: Embodiments of the present invention are directed to a plurality of substantially spherical microspheres comprising at least one API substantially dispersed in at least one polymer and a lyoprotectant on an outside surface of the plurality of substantially spherical microspheres, wherein the plurality of substantially spherical microspheres have a D99[num] particle diameter of less than about 10 ?m; a D90[num] circularity value of from about 0.8 to about 1.0; and comprise API in a weight of about 20 to about 40 wt. % of the polymer. Other embodiments relate to injectable compositions comprising such microspheres and methods of treating a number of conditions by administering such injectable compositions to a subject.
    Type: Application
    Filed: December 23, 2020
    Publication date: June 24, 2021
    Inventors: Jeffrey Missling, Emily R. Rolfes Meyering, Henry Meyer, Celeste Ondich
  • Patent number: 10925883
    Abstract: Embodiments of the present invention are directed to a plurality of substantially spherical microspheres comprising at least one API substantially dispersed in at least one polymer and a lyoprotectant on an outside surface of the plurality of substantially spherical microspheres, wherein the plurality of substantially spherical microspheres have a D99[num] particle diameter of less than about 10 m; a D90[num] circularity value of from about 0.8 to about 1.0; and comprise API in a weight of about 20 to about 40 wt. % of the polymer. Other embodiments relate to injectable compositions comprising such microspheres and methods of treating a number of conditions by administering such injectable compositions to a subject.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 23, 2021
    Assignee: SpineThera
    Inventors: Jeffrey Missling, Emily R. Rolfes Meyering, Henry Meyer, Celeste Ondich
  • Patent number: 10850235
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. The method may include the steps of withdrawing fluid comprising CSF, filtering the volume into permeate and retentate by passing the fluid through a tangential flow filter, and returning the permeate to the subject. During operation of the system, various parameters may be modified, such as flow rate.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: December 1, 2020
    Assignee: MINNETRONIX, INC.
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe
  • Publication number: 20200237979
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Application
    Filed: April 17, 2020
    Publication date: July 30, 2020
    Applicant: MINNETRONIX, INC.
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Publication number: 20200170505
    Abstract: The invention relates to a method for determining the occurrence of a vascular collapse of a blood vessel in or on the eye. According to the invention, it is proposed that the vascular collapse be determined from a measured temporal change of blood flow in the blood vessel.
    Type: Application
    Filed: December 29, 2017
    Publication date: June 4, 2020
    Inventor: Rolf MEYER-SCHWICKERATH
  • Patent number: 10632237
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: April 28, 2020
    Assignee: MINNETRONIX, INC.
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Publication number: 20190269698
    Abstract: Embodiments of the present invention are directed to a plurality of substantially spherical microspheres comprising at least one API substantially dispersed in at least one polymer and a lyoprotectant on an outside surface of the plurality of substantially spherical microspheres, wherein the plurality of substantially spherical microspheres have a D99[num] particle diameter of less than about 10 m; a D90[num] circularity value of from about 0.8 to about 1.0; and comprise API in a weight of about 20 to about 40 wt. % of the polymer. Other embodiments relate to injectable compositions comprising such microspheres and methods of treating a number of conditions by administering such injectable compositions to a subject.
    Type: Application
    Filed: October 28, 2016
    Publication date: September 5, 2019
    Inventors: Jeffrey Missling, Emily R. Rolfes Meyering, Henry Meyer, Celeste Ondich
  • Patent number: 9987115
    Abstract: Various embodiments of an implant devices and systems are provided. The implant devices can include a mesh or implant encapsulated or otherwise coated, in whole or in part, with a film or coating. The coating or film can include methylcellulose or ethylcellulose to provide tissue regeneration as a hydrogel, while also providing a stiff polymer film when dry.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: June 5, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Benjamin Y. Arcand, James A. Kazmierkoski, Dean W. Hacker, Emily R. Rolfes Meyering
  • Patent number: 9949811
    Abstract: Various embodiments of a mesh or implant system are provided for treating pelvic conditions such as incontinence, vaginal prolapsed, and other conditions caused by muscle and ligament weakness. Embodiments of the implants can include a material, substrate, configuration or coating adapted to provide immediate or timed release of various therapeutic agents or drugs to treat the surrounding tissue.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: April 24, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: John R. Frigstad, Thomas Q. Dinh, Emily R. Rolfes-Meyering
  • Patent number: 9669436
    Abstract: A cleaning apparatus for microsurgical instruments has a flush chamber closed off at one end by a first plug adapted to liquid-tightly grip one end of the instrument, allowing a portion of the instrument to extend past the first plug and out of the flush chamber. The other end of the flush chamber is closed off by a second plug having an inlet port. Liquid injected through the inlet port on the second plug passes through an internal passageway formed in the instrument and exits the instrument through the portion that extends past the first plug. In another embodiment the instrument has an internal passageway and an end cap through which flushing ports are formed which communicate with the passageway. A first plug having an inlet port is liquid-tightly attached to the end cap and liquid injected into the first plug passes through the plug, through the flushing ports and through the passageway to clean detritus from the instrument.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: June 6, 2017
    Assignee: Asico, LLC
    Inventor: Rolf Meyer
  • Patent number: 9649405
    Abstract: Compositions, systems, and methods for the treatment of pelvic tissue conditions that include use of a silk fibroin-containing hydrogel composition are disclosed. The composition may include a water-soluble fibroin and a water-soluble crosslinkable polymer that can be used as a pre-formed hydrogel, and/or delivered to a pelvic tissue site and crosslinked in situ to form a hydrogel. The composition may promote tissue closure, such as vaginal wound or fistula closure; and/or enhance attachment or anchoring of a pelvic implant to a pelvic tissue. The composition may be a hydrogel that is delivered to a pelvic tissue site, formed at the site in situ, and/or associated with a portion of the implant (e.g., a mesh implant) via a tether or implant extension portion, thereby providing improved immobilization of the implant. Systems or kits that include the composition and/or a delivery needle or insertion tool are also described.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: May 16, 2017
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Emily R. Rolfes Meyering, Benjamin Y. Arcand
  • Publication number: 20170035950
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.
    Type: Application
    Filed: August 5, 2016
    Publication date: February 9, 2017
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe, Jack Mondry
  • Publication number: 20170035998
    Abstract: Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. The method may include the steps of withdrawing fluid comprising CSF, filtering the volume into permeate and retentate by passing the fluid through a tangential flow filter, and returning the permeate to the subject. During operation of the system, various parameters may be modified, such as flow rate.
    Type: Application
    Filed: June 9, 2016
    Publication date: February 9, 2017
    Inventors: Emily Rolfes Meyering, Gary Seim, Abhi Vase, Ben Krehbiel, Blake Hedstrom, Aaron McCabe
  • Patent number: 9539079
    Abstract: Described are pelvic implants, systems including the implant and a delivery tool, and methods for the treatment of incontinence or prolapse. The implant has an expansion member associated with a support portion and a tensioning member along an extension portion of the implant. Systems and methods for treating incontinence or prolapse that include a composition having non-absorbable fibers of different sizes that can be applied to and set on an implant are also provided.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: January 10, 2017
    Inventor: Emily R. Rolfes Meyering
  • Publication number: 20170000361
    Abstract: Disclosed embodiments include methods and devices for introducing a sheath into a human or animal subject. Some embodiments include a puncture tool that may simultaneously deliver a sheath and a needle to a desired anatomical location. The needle may be removed and the sheath may be used to define a space that may be used to conduct a procedure.
    Type: Application
    Filed: June 16, 2016
    Publication date: January 5, 2017
    Inventors: Emily Rolfes Meyering, Elizabeth Scheurer, Aaron McCabe