Patents by Inventor Rolf O. Ehrhardt

Rolf O. Ehrhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating psoriasis
    Patent number: 9078876
    Abstract: Methods and compositions are provided for the creation and screening of non-human animal models having many of the histologic characteristics of human psoriasis. Immunocompromised host animals are injected with a purified population of CD45Rb positive cells, which are tolerant of the host major histocompatibility antigens, but are mismatched at one or more minor antigens. The injected cells are stimulated with a pro-inflammatory cytokine, e.g. IL-12, and a polyclonal activating agent. The injected animals develop a chronic skin disorder that includes histological features observed in human psoriasis, e.g. rete pegs, severe acanthosis and infiltration of Th1 cells into the dermis.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: July 14, 2015
    Assignee: Abbvie Biotherapeutics, Inc.
    Inventors: Rolf O. Ehrhardt, Kenneth Hong
  • Method for treating psoriasis
    Patent number: 9072725
    Abstract: Methods of treating a patient suffering from psoriasis are disclosed, comprising administration of an antibody binding to interleukin-12 (IL-12).
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: July 7, 2015
    Assignee: Abbvie Biotherapeutics, Inc.
    Inventors: Rolf O. Ehrhardt, Kenneth Hong
  • METHOD FOR TREATING PSORIASIS
    Publication number: 20140314756
    Abstract: Methods of treating a patient suffering from psoriasis are disclosed, comprising administration of an antibody binding to interleukin-12 (IL-12).
    Type: Application
    Filed: July 1, 2014
    Publication date: October 23, 2014
    Inventors: Rolf O. Ehrhardt, Kenneth Hong, Cary Queen