Patents by Inventor Rolf Stahel

Rolf Stahel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor-specific antibodies and antigen
    Patent number: 5614373
    Abstract: The invention relates to a novel epitope of 180,000 daltons for the NCAM antigen and a monoclonal antibody, SEN7, directed against this antigen, and their use in diagnosis and therapy of small-cell carcinoma of the lung. The antibody SEN7 reacts significantly more selectively than previously known antibodies with cells of small-cell carcinoma of the lung, and binds with high avidity. In particular, no reaction occurs with leucocytes or healthy kidney or lung epithelial cells. The novel antigen is dominantly expressed by cells of small-cell carcinoma of the lung with a high copy number.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: March 25, 1997
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventor: Rolf Stahel