Patents by Inventor Rolf Wagner

Rolf Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial compounds
    Publication number: 20050159423
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Application
    Filed: January 21, 2004
    Publication date: July 21, 2005
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Robert Keyes, Xenia Searle, Rolf Wagner
  • Anti-infective agents
    Publication number: 20050107364
    Abstract: Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.
    Type: Application
    Filed: August 24, 2004
    Publication date: May 19, 2005
    Inventors: Douglas Hutchinson, John Bellettini, David Betebenner, Richard Bishop, Thomas Borchardt, Todd Bosse, Russell Cink, Charles Flentge, Bradley Gates, Brian Green, Mira Hinman, Peggy Huang, Larry Klein, Allan Krueger, Daniel Larson, M. Leanna, Dachun Liu, Darold Madigan, Keith McDaniel, John Randolph, Todd Rockway, Teresa Rosenberg, Kent Stewart, Vincent Stoll, Rolf Wagner, Ming Yeung
  • Antibacterial compounds
    Patent number: 6818654
    Abstract: Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: November 16, 2004
    Assignee: Abbott Laboratories
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Linda Lynch, Zhenkun Ma, Christopher Motter, Teresa Rosenberg, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong
  • Antibacterial compounds
    Publication number: 20040072817
    Abstract: Antibacterials having formula (I) 1
    Type: Application
    Filed: March 12, 2003
    Publication date: April 15, 2004
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Linda Lynch, Zhenkun Ma, Christopher Motter, Teresa Rosenberg, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong
  • Antibacterial compounds
    Publication number: 20030232818
    Abstract: Antibacterials having formula (I) 1
    Type: Application
    Filed: March 12, 2003
    Publication date: December 18, 2003
    Inventors: David Anderson, Bruce Beutel, Todd D. Bosse, Richard Clark, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Todd Matthew Hansen, Mira Hinman, Douglas Kalvin, Daniel P. Larson, Linda Lynch, Zhenkun Ma, Christopher Motter, Fabio Palazzo, Teresa Rosenberg, Tamara Rehm, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong, Tianyuan Zhang
  • Reheater door of a spinning device
    Patent number: 6312245
    Abstract: The invention provides a reheater door of a spinning device, which door is constructed so as to facilitate relatively easy access to the spinning nozzle plate as well as enable suction removal of vaporizable compounds and prevention of substantial cooling even when the door is open.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: November 6, 2001
    Assignee: Lurgi Zimmer Aktiengesellschaft
    Inventors: Heinz-Dieter Beeck, Guenter Koschinek, Werner Mrose, Rolf Wagner
  • Macrocyclic amide and urea immunomodulators
    Patent number: 5731320
    Abstract: Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: March 24, 1998
    Assignee: Abbott Laboratories
    Inventors: Rolf Wagner, Jay R. Luly, Yat Sun Or
  • Macrocyclic immunomodulators
    Patent number: 5708002
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: January 13, 1998
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, Megumi Kawai, Yat Sun Or, Paul Wiedeman, Rolf Wagner
  • Macrolide immunomodulators
    Patent number: 5672605
    Abstract: Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of treating immunomodulatory disorders are disclosed.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: September 30, 1997
    Assignee: Abbott Laboratories
    Inventors: Yat Sun Or, Jay R. Luly, Rolf Wagner
  • Marcrocyclic amide and urea immunomodulators
    Patent number: 5643918
    Abstract: Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: July 1, 1997
    Assignee: Abbott Laboratories
    Inventors: Rolf Wagner, Jay R. Luly, Yat Sun Or
  • Macrocyclic immunomodulators
    Patent number: 5604294
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein Y is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same and methods of their use.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: February 18, 1997
    Inventors: Jay R. Luly, Megumi Kawai, Yat S. Or, Paul E. Wiedeman, Rolf Wagner
  • Marcolide immunomodulators
    Patent number: 5583139
    Abstract: Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of treating immunomodulatory disorders are disclosed.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: December 10, 1996
    Assignee: Abbott Laboratories
    Inventors: Yat Sun Or, Jay R. Luly, Rolf Wagner
  • Macrocyclic amide and urea immunomodulators
    Patent number: 5563172
    Abstract: Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: October 8, 1996
    Assignee: Abbott Laboratories
    Inventors: Rolf Wagner, Jay R. Luly, Yat S. Or
  • Macrocyclic immunomodulators
    Patent number: 5561228
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a group having the formula ##STR2## as well as pharmaceutical compositions containing the same.
    Type: Grant
    Filed: March 7, 1994
    Date of Patent: October 1, 1996
    Assignee: Abbott Laboratories
    Inventors: Yat S. Or, Jay R. Luly, Megumi Kawai, Rolf Wagner, Paul E. Wiedeman
  • Macrolide immunomodulators
    Patent number: 5527907
    Abstract: Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of treating immunomodulatory disorders are disclosed.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: June 18, 1996
    Assignee: Abbott Laboratories
    Inventors: Yat S. Or, Jay R. Luly, Rolf Wagner
  • Analogs of tyrosine sulfate or tyrosine phosphate containing peptides
    Patent number: 5508437
    Abstract: Analogs of Tyrosine Sulfate or Tyrosine Phosphate containing peptides, the novel intermediate compounds used in the preparation of these analogs, as well as a method for suppressing appetite in subjects by administering to the subject an effective amount of CCK analog wherein one or more of any Tyrosine Sulfate present is substituted with a radical of the invention.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: April 16, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Waleed Danho, Jefferson W. Tilley, Joseph Triscari, Rolf Wagner
  • Macrocyclic immunomodulators
    Patent number: 5457111
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
    Type: Grant
    Filed: November 9, 1993
    Date of Patent: October 10, 1995
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, Megumi Kawai, Yat S. Or, Paul Wiedeman, Rolf Wagner
  • Hexapeptide anaphylatoxin-receptor ligands
    Patent number: 5386011
    Abstract: Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states.Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: January 31, 1995
    Assignee: Abbott Laboratories
    Inventors: Paul E. Wiedeman, Megumi Kawai, Jay R. Luly, Yat S. Or, Rolf Wagner
  • Intermediates for analogs of tyrosine sulfate or tyrosine phosphate containing peptides
    Patent number: 5296608
    Abstract: Analogs of Tyrosine Sulfate or Tyrosine Phosphate containing peptides, the novel intermediate compounds used in the preparation of these analogs, as well as a method for suppressing appetite in subjects by administering to the subject an effective amount of CCK analog wherein one or more of any Tyrosine Sulfate present is substituted with a radical of the invention.
    Type: Grant
    Filed: April 9, 1992
    Date of Patent: March 22, 1994
    Assignee: Hoffman-La Roche Inc.
    Inventors: Waleed Danho, Jefferson W. Tilley, Joseph Triscari, Rolf Wagner
  • Analogs of tyrosine sulfate or tyrosine phosphate containing peptides
    Patent number: 5182263
    Abstract: Analogs of Tyrosine Sulfate or Tyrosine Phosphate containing peptides, the novel intermediate compounds used in the preparation of these analogs, as well as a method for suppressing appetite in subjects by administering to the subject an effective amount of CCK analog wherein one or more of any Tyrosine Sulfate present is substituted with a radical of the invention.
    Type: Grant
    Filed: July 18, 1991
    Date of Patent: January 26, 1993
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Waleed Danho, Jefferson W. Tilley, Joseph Triscari, Rolf Wagner