Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.

Abstract: A polymer having the following monomers in polymerized form (in weight %): A) 49-60% of a first monomer which is selected from the group consisting of methyl acrylate, methyl methacrylate, ethyl acrylate, ethyl methacrylate, C3-alkyl acrylate, C3-alkyl methacrylate, C4-alkyl acrylate, C4-alkyl methacrylate and mixtures thereof, B) 30-40% methacrylic acid, C) 4-15% acrylic acid, and D) 0.02-0.30% of a crosslinking agent having at least two allyl moieties, wherein the sum of the amounts of monomers A to D is 100%. A hair styling composition containing the polymer and use of the polymer or of the hair styling composition for styling hair also are disclosed.

Abstract: A polymer having the following monomers in polymerized form (in weight %): A) 49-60% of a first monomer which is selected from the group consisting of methyl acrylate, methyl methacrylate, ethyl acrylate, ethyl methacrylate, C3-alkyl acrylate, C3-alkyl methacrylate, C4-alkyl acrylate, C4-alkyl methacrylate and mixtures thereof, B) 30-40% methacrylic acid, C) 4-15% acrylic acid, and D) 0.02-0.30% of a crosslinking agent having at least two allyl moieties, wherein the sum of the amounts of monomers A to D is 100%. A hair styling composition containing the polymer and use of the polymer or of the hair styling composition for styling hair also are disclosed.

Abstract: An eye surgery apparatus has imaging optics for generating an observation image of a patient eye. A device determines the azimuthal orientation of the patient eye with respect to a reference which is fixed with respect to the patient eye. The device includes a display unit for simultaneously displaying a section of an observation image of the eye and a reference image thereof. An input interface permits an observer to move the displayed section of the observation image relative to the displayed section of the reference image. A measuring system determines the azimuthal orientation of the observation image and reference image. A computer program calculates the center of the limbus of the observation image and reference image. The display unit displays the pixels of the observation image of the patient eye with polar coordinates. The pixels of the reference image of the patient eye are displayed with polar coordinates.

Abstract: The invention relates to a polymer suited for modifying the styling performance and the rheology of a cosmetic preparation, a composition thereof, a method of making it as well as the use of said polymer and the composition respectively. The copolymer comprises at least one non-ionic ethylenically unsaturated C1-C4 (meth)acrylate as monomer A; an ethylenically unsaturated monomer B having as hydrogen bond donor an amide group, said ethylenically unsaturated monomer B being an ethylenically unsaturated monomer having a cyclic amide moiety, as monomer B1 and/or, an ethylenically unsaturated monomer having an acyclic amide group, as monomer B2; at least one ethylenically unsaturated carboxylic acid as monomer C; a macromonomer D; optionally at least one cross-linker E; and optionally at least one further monomer F.

Abstract: An eye surgery apparatus has imaging optics for generating an observation image of a patient eye. A device determines the azimuthal orientation of the patient eye with respect to a reference which is fixed with respect to the patient eye. The device includes a display unit for simultaneously displaying a section of an observation image of the eye and a reference image thereof. An input interface permits an observer to move the displayed section of the observation image relative to the displayed section of the reference image. A measuring system determines the azimuthal orientation of the observation image and reference image. A computer program calculates the center of the limbus of the observation image and reference image. The display unit displays the pixels of the observation image of the patient eye with polar coordinates. The pixels of the reference image of the patient eye are displayed with polar coordinates.

Abstract: The invention relates to a polymer suited for modifying the styling performance and the rheology of a cosmetic preparation, a composition thereof, a method of making it as well as the use of said polymer and the composition respectively. The copolymer comprises at least one non-ionic ethylenically unsaturated C1-C4 (meth)acrylate as monomer A; an ethylenically unsaturated monomer B having as hydrogen bond donor an amide group, said ethylenically unsaturated monomer B being an ethylenically unsaturated monomer having a cyclic amide moiety, as monomer B1 and/or, an ethylenically unsaturated monomer having an acyclic amide group, as monomer B2; at least one ethylenically unsaturated carboxylic acid as monomer C; a macromonomer D; optionally at least one cross-linker E; and optionally at least one further monomer F.

Abstract: The present invention relates to a method for producing polymers by radically polymerizing a mixture comprising 99.99 to 10% by weight of at least one ?,?-ethylenically unsaturated compound with at least one cationogenic and/or cationic group per molecule, 0 to less than 25% by weight of at least one monoethylenically unsaturated amide-group-containing compound different from a) and also 0.01 to 5% by weight of a crosslinker using at least two different water-insoluble initiators.

Abstract: The present invention relates to precipitation polymers which comprise, in copolymerized form, 80 to 99.9% by weight of at least one nonionic water-soluble monomer a) and 0.1 to 20% by weight of a monomer b) carrying amide or urea groups. The invention further relates to the use of these polymers as rheology modifiers for in particular aqueous compositions and as rheology-modifying setting agents in hair cosmetics. The invention further relates to aqueous compositions comprising these polymers.

Abstract: The present invention relates to new anionic associative rheology modifiers, their manufacture and application.

Abstract: The present invention relates to new anionic associative rheology modifiers, their manufacture and application.

Abstract: The invention relates to a method for the production of a metallic pipeline with firmly adherent plastics sheathing, where, by means of a plasma treatment or by means of a gas-burner flame, an activated surface is generated on a metal pipe, where the exposure time of the surface is less than 3 seconds, and a plastics sheathing is applied to the activated naked surface of the metal pipe and, at the juncture of application of the sheathing, the temperature of the surface of the metal pipe is below 80° C.

Abstract: The present invention relates to a method for producing polymers by radically polymerizing a mixture comprising 99.99 to 10% by weight of at least one ?,?-ethylenically unsaturated compound with at least one cationogenic and/or cationic group per molecule, 0 to less than 25% by weight of at least one monoethylenically unsaturated amide-group-containing compound different from a) and also 0.01 to 5% by weight of a crosslinker using at least two different water-insoluble initiators.

Abstract: The present invention relates to improved methods for synthesising cyproterone acetate (17?-Acetoxy-6-chloro-1?, 2(?-methylene-4,6-pregnadiene-3,20-dione) from solasodine.

Abstract: Compounds of the formula ##STR1## wherein A is phenyl; 4-hydroxy-phenyl; 2- or 3-thienyl; cyclohexyl; cyclohexen-1-yl; cyclohexa-1, 4-dien-1-yl; or 3,4-disubstituted phenyl, where the substituents may be identical to or different from each other and are selected from the group consisting of chlorine, hydroxyl or methoxy; andR is an aliphatic, cycloaliphatic; aromatic or heterocyclic group of diverse types;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as antibiotics.