Patents by Inventor Rom Leidner

Rom Leidner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for detecting gastrointestinal and other cancers
    Patent number: 11136629
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: October 5, 2021
    Assignee: Case Western Reserve University
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS
    Publication number: 20190390285
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Application
    Filed: September 9, 2019
    Publication date: December 26, 2019
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • Methods and compositions for detecting gastrointestinal and other cancers
    Patent number: 10450615
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: October 22, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS
    Publication number: 20190241973
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS
    Publication number: 20170204470
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Application
    Filed: January 23, 2017
    Publication date: July 20, 2017
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • Methods and compositions for detecting gastrointestinal and other cancers
    Patent number: 9580754
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder. Nucleic acid sequences for regions of vimentin that are found to be differentially methylated are described. The present disclosure further describes bisulfite-converted vimentin template DNA sequences. Oligonucleotide primer sequences for use in assays (e.g., methylation-sensitive PCR assays or HpaII assays) designed to detect the methylation status of the vimentin gene are also described.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: February 28, 2017
    Assignee: Case Western Reserve University
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • Methods and compositions for detecting gastrointestinal and other cancers
    Patent number: 8415100
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: April 9, 2013
    Assignee: Case Western Reserve University
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner
  • METHODS AND COMPOSITIONS FOR DETECTING GASTROINTESTINAL AND OTHER CANCERS
    Publication number: 20120094287
    Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 19, 2012
    Inventors: Sanford D. Markowitz, Joseph Willis, Amitabh Chak, Rom Leidner