Patents by Inventor Roman Chicz

Roman Chicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE EPITOPES RECOGNIZED BY DISEASE PROMOTING CD4+ T LYMPHOCYTES
    Publication number: 20070142622
    Abstract: The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The invention includes peptides derived from the IA-2 polypeptide by such a method, altered peptide ligands, and methods of therapy involving the use of altered peptide ligands.
    Type: Application
    Filed: February 2, 2007
    Publication date: June 21, 2007
    Applicants: MGI PHARMA Biologics, Inc., King's College London
    Inventors: Mark Peakman, Roman Chicz
  • PEPTIDE EPITOPES RECOGNIZED BY DISEASE PROMOTING CD4+ T LYMPHOCYTES
    Publication number: 20070135618
    Abstract: The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The invention includes peptides derived from the IA-2 polypeptide by such a method, altered peptide ligands, and methods of therapy involving the use of altered peptide ligands.
    Type: Application
    Filed: February 2, 2007
    Publication date: June 14, 2007
    Applicants: MGI PHARMA Biologics, Inc., King's College London
    Inventors: Mark Peakman, Roman Chicz
  • Compositions and methods for treating human papillomavirus mediated disease
    Publication number: 20060247190
    Abstract: The invention includes methods of treating an HPV-mediated disease by administration to an individual of a pharmaceutical composition comprising a nucleic acid that encodes a polypeptide comprising an epitope of a naturally occurring HPV protein. The methods include the selection of individuals for treatment with the composition according to the age of the recipient, as well as the use of the composition to elicit a cross-reactive anti-HPV immune response.
    Type: Application
    Filed: October 16, 2003
    Publication date: November 2, 2006
    Inventors: Kathleen Beach, Mary Hedley, Robert Urban, Roman Chicz
  • Nucleic acids encoding polyepitope polypeptides
    Publication number: 20050100928
    Abstract: The invention provides nucleic acids encoding polyepitope polypeptides containing multiple epitopes from one or more proteins. The polyepitope polypeptides are useful as treatments for pathogenic agents or tumors.
    Type: Application
    Filed: January 5, 2004
    Publication date: May 12, 2005
    Inventors: Mary Hedley, Robert Urban, Roman Chicz