Patents by Inventor Roman Gerber AESCHBACHER

Roman Gerber AESCHBACHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic path to pharmaceutically acceptable Vismodegib
    Patent number: 10343998
    Abstract: The present invention relates to a new route of synthesis to obtain pharmaceutically acceptable Vismodegib. In addition, besides the synthesis also suitable pharmaceutical compositions and the use of the compound for the treatment of basal-cell carcinomas are disclosed.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: July 9, 2019
    Assignee: AZAD PHARMACEUTICAL INGREDIENTS AG
    Inventors: Christian Manfred Frech, Pasquale Gabriele Grieco, Christine Aebersold, Patrick Müller, Jan-Erik Ingenhoff, Miriam Oberholzer, Viktorya Rstakyan, Roman Gerber Aeschbacher
  • PROCESS FOR THE SYNTHESIS OF STABLE AMORPHOUS IBRUTINIB
    Publication number: 20190040070
    Abstract: Disclosed herein is a new route of synthesis and a new stable amorphous form of ibrutinib. Also disclosed are pharmaceutical compositions, oral dosage forms and the use of the amorphous ibrutinib in the treatment of mantle cell lymphoma or chronic lymphocytic leukemia.
    Type: Application
    Filed: February 8, 2017
    Publication date: February 7, 2019
    Inventors: Thomas MAIER, Inna KARAPETYAN, Alvard ARAKELYAN, Tamara MARGARYAN, Vardan SARGSYAN, Heghine STEPANYAN, Hermine ABOVYAN, Roman GERBER AESCHBACHER, Sven HAFERKAMP
  • Route Of Synthesis For Opicapone
    Publication number: 20180370958
    Abstract: The present invention relates to a new route of synthesis for obtaining Opicapone ((4Z)-4-[3-(2,5-dichloro-4,6-dimethyl-1-oxidopyridin-1-ium-3-yl)-2H-1,2,4-oxadia-zol-5-ylidene]-2-hydroxy-6-nitrocyclohexa-2,5-dien-1-one), new intermediates in the reaction path and the new substance 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidoyl chloride.
    Type: Application
    Filed: June 27, 2018
    Publication date: December 27, 2018
    Inventors: Christian Frech NABOLD, Christine AEBERSOLD, Pasquale Gabriele GRIECO, Roman Gerber AESCHBACHER
  • Synthetic Path To Pharmaceutically Acceptable Vismodegib
    Publication number: 20180273477
    Abstract: The present invention relates to a new route of synthesis to obtain pharmaceutically acceptable Vismodegib. In addition, besides the synthesis also suitable pharmaceutical compositions and the use of the compound for the treatment of basal-cell carcinomas are disclosed.
    Type: Application
    Filed: March 26, 2018
    Publication date: September 27, 2018
    Inventors: Christian Manfred FRECH, Pasquale Gabriele GRIECO, Christine AEBERSOLD, Patrick MÜLLER, Jan-Erik INGENHOFF, Miriam OBERHOLZER, Viktorya RSTAKYAN, Roman Gerber AESCHBACHER