Patents by Inventor Roman MELEDIN

Roman MELEDIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UBIQUITIN HIGH AFFINITY PEPTIDES, AND METHODS OF USING SAME, AND IDENTIFYING SAME
    Publication number: 20230340027
    Abstract: The present invention, in some embodiments, is directed to a peptide having increased binding affinity to ubiquitin (Ub). Further provided is a pharmaceutical composition including the peptide of the invention, a method of using same, such as for treating a subject afflicted with cancer, and a method for identifying peptides having increased binding affinity to Ub.
    Type: Application
    Filed: June 8, 2021
    Publication date: October 26, 2023
    Inventors: Ashraf BRIK, Roman MELEDIN, Ganga Babu VAMISETTI
  • A CD25-BIASED ANTI-IL-2 ANTIBODY
    Publication number: 20230303680
    Abstract: The invention provides a human IL-2 (hlL-2)-specific monoclonal antibody, wherein a complex of hlL-2 and the monoclonal induces IL-2 signalling preferentially via CD25 and the trimeric IL-2R. The invention further provides a pharmaceutical composition comprising hlL-2 and said hlL-2-mAb for use treating inflammatory disease.
    Type: Application
    Filed: August 18, 2021
    Publication date: September 28, 2023
    Applicant: UNIVERSITÄT ZÜRICH
    Inventors: Onur BOYMAN, Ufuk KARAKUS, Miro RAEBER, Roman MELEDIN, Robert MAKA