Patents by Inventor Roman Perez

Roman Perez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10569253
    Abstract: The invention provides biocomposites alginate/chitosan beads integrated with magnetite nanoparticles and modified-surface magnetite derivate created and designed to remove from environmental waters and aquatic systems different types of organic persistent compounds such as benzophenone-3 (oxybenzone).
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: February 25, 2020
    Assignee: University of Puerto Rico
    Inventors: Felix Roman Velazquez, Victor Fernandez Alos, Oscar Perales Perez
  • Patent number: 10322210
    Abstract: The present invention relates to a preparation method for core-shell structured fibrous scaffolds, and more specifically to preparing a core part composition and a shell part composition that each have different constitutions by adding calcium phosphate cement and a protein, drug of combination thereof to alginate solution, and then inserting the above core part composition and shell part composition to internal and external nozzle of concentric nozzle respectively to inject into calcium ion aqueous solution and thereby hardening them, thus preparing core-shell structured rapidly setting Alg/?-TCP scaffolds capable of controllably releasing a protein or drug.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: June 18, 2019
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY
    Inventors: Hae-Won Kim, Roman Perez
  • Patent number: 9663429
    Abstract: The present invention relates to compounds of pharmaceutical interest. More particularly, it relates to compounds of formula (I), to processes for obtaining thereof, to the intermediates of their synthesis and processes for obtaining the latter. The compounds of formula (I) have a certain affinity with the vitamin D receptor, they are active in a similar order to 1,25?-dihydroxyvitamin D3 (1,25D), with the advantage of producing less or no hypercalcemia.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: May 30, 2017
    Assignees: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, UNIVERSIDADE DA CORUNA, SERVIZO GALEGO DE SAUDE (SERGAS)
    Inventors: Roman Perez Fernandez, Samuel Seoane Ruzo, Antonio Mouriño Mosquera, Miguel Maestro Saavedra, Jose Esteban Castelao Fernandez, Pranjal Gogoi
  • Publication number: 20160297731
    Abstract: The present invention relates to compounds of pharmaceutical interest. More particularly, it relates to compounds of formula (I), to processes for obtaining thereof, to the intermediates of their synthesis and processes for obtaining the latter. The compounds of formula (I) have a certain affinity with the vitamin D receptor, they are active in a similar order to 1,25?-dihydroxyvitamin D3 (1,25D), with the advantage of producing less or no hypercalcemia.
    Type: Application
    Filed: November 19, 2014
    Publication date: October 13, 2016
    Inventors: Roman PEREZ FERNANDEZ, Samuel SEOANE RUZO, Antonio MOURINO MOSQUERA, Miguel MAESTRO SAAVEDRA, Jose Esteban CASTELAO FERNANDEZ, Pranjal GOGOI
  • Publication number: 20160166608
    Abstract: One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml.
    Type: Application
    Filed: July 10, 2015
    Publication date: June 16, 2016
    Inventors: Frank G. Pilkiewicz, Roman PEREZ-SOLER, Yiyu ZOU, Walter R. PERKINS, Jin K. LEE, Vladimir MALININ
  • Publication number: 20160000835
    Abstract: The present invention relates to a method for isolating stem cells comprising preparing a cell suspension from uterine cervix tissue, to the stem cells isolated by said method, and to the conditioned medium obtained from the culture of said stem cells. The invention also encompasses the use of said stem cells or conditioned medium for treating or preventing cancer, precancerous lesions, inflammatory diseases, autoimmune diseases, chronic pathologies or infectious diseases, diseases associated to tissue loss, or for use in diagnostic, prognostic or treatment of fertility disorders, as well as for cosmetic treatment.
    Type: Application
    Filed: February 24, 2014
    Publication date: January 7, 2016
    Inventors: Francisco José VIZOSO PIÑEIRO, Román PÉREZ FERNÁNDEZ, Noemí EIRÓ DÍAZ
  • Patent number: 9107824
    Abstract: One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: August 18, 2015
    Assignee: Insmed Incorporated
    Inventors: Frank G. Pilkiewicz, Roman Perez-Soler, Yiyu Zou, Walter R. Perkins, Jin K. Lee, Vladimir Malinin
  • Publication number: 20140186413
    Abstract: The present invention relates to a preparation method for core-shell structured fibrous scaffolds, and more specifically to preparing a core part composition and a shell part composition that each have different constitutions by adding calcium phosphate cement and a protein, drug of combination thereof to alginate solution, and then inserting the above core part composition and shell part composition to internal and external nozzle of concentric nozzle respectively to inject into calcium ion aqueous solution and thereby hardening them, thus preparing core-shell structured rapidly setting Alg/?-TCP scaffolds capable of controllably releasing a protein or drug.
    Type: Application
    Filed: September 25, 2013
    Publication date: July 3, 2014
    Inventors: Hae-Won KIM, Roman PEREZ
  • Publication number: 20130225690
    Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Application
    Filed: September 20, 2012
    Publication date: August 29, 2013
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman Perez-Soler, Yi-He Ling
  • Patent number: 8283382
    Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: October 9, 2012
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman Perez-Soler, Yi-He Ling
  • Publication number: 20110195103
    Abstract: Cosmetic or dermopharmaceutical compositions containing Pseudoalteromonas ferment extract for the treatment and/or care of the skin, scalp and/or nails, preferably to improve the barrier function of the skin, scalp and/or nails, and specifically for the treatment and/or care of those conditions, disorders and/or pathologies of the skin, scalp and/or nails associated with an alteration in the keratinization process.
    Type: Application
    Filed: October 9, 2009
    Publication date: August 11, 2011
    Applicant: LIPOTEC, S.A.
    Inventors: Roman Perez Arcas, Carla Oncins Bergas, Jose Maria Garcia Anton
  • Publication number: 20100324148
    Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Application
    Filed: May 26, 2010
    Publication date: December 23, 2010
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman Perez-Soler, Yi-He Ling
  • Publication number: 20100226919
    Abstract: The present invention relates to combinations of PM02734 with EGFR tyrosine kinase inhibitors, and the use of these combinations in the treatment of cancer.
    Type: Application
    Filed: October 17, 2008
    Publication date: September 9, 2010
    Applicants: Pharma Mar, S.A., ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Román Pérez-Soler, Yi-He Ling, José Maria Jimeno Donaque, Yi-Yu Zou
  • Patent number: 7745494
    Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Grant
    Filed: April 12, 2006
    Date of Patent: June 29, 2010
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman Perez-Soler, Yi-He Ling
  • Publication number: 20100055047
    Abstract: The present invention is directed to methods for treating bronchial premalignancy and/or lung cancer in a subject comprising administering to the subject an aerosolized pharmaceutical composition comprising a therapeutically effective amount of 5-azacytidine and a pharmaceutically acceptable carrier. The present invention is also directed to methods for decreasing the likelihood of occurrence of bronchial premalignancy and/or lung cancer in a subject comprising administering to the subject an aerosolized pharmaceutical composition comprising a prophylactically effective amount of 5-azacytidine and a pharmaceutically acceptable carrier. The present invention is also directed to pharmaceutical compositions for treating bronchial premalignancy and/or lung cancer in a subject comprising a therapeutically effective amount of 5-azacytidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 24, 2009
    Publication date: March 4, 2010
    Inventors: Yiyu Zou, Roman Perez-Soler
  • Publication number: 20090239952
    Abstract: The invention provides methods and compositions tor treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (BGKR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Application
    Filed: May 14, 2009
    Publication date: September 24, 2009
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman PEREZ-SOLER, Yi-He LING
  • Publication number: 20090209652
    Abstract: The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
    Type: Application
    Filed: April 12, 2006
    Publication date: August 20, 2009
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Roman Perez-Soler, Yi-He Ling
  • Patent number: 7557090
    Abstract: The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3? of the sugar moiety or modified or unmodified alkyl-aromatic ring substitutions at the C-4? of the sugar moiety. It also discloses novel methods for the preparation of sugar substrates and methods for the preparation of anthracycline antibiotics. These anthracycline analogs show high cytotoxicity in vitro against several tumor cell lines.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: July 7, 2009
    Assignee: Houston Pharmaceuticals, Inc.
    Inventors: Waldemar Priebe, Izabella Fokt, Teresa Prezewloka, Marta Krawczyk, Piotr Skibicki, Grzegorz Grynkiewicz, Roman Perez-Soler
  • Publication number: 20090130194
    Abstract: In one aspect, the present invention relates to methods of treating cancer in a patient comprising administering intravenously to a patient in need thereof a cancer treating effective amount of a lipid-complexed platinum compound composition wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml.
    Type: Application
    Filed: May 16, 2008
    Publication date: May 21, 2009
    Applicant: Transave, Inc.
    Inventors: Frank G. Pilkiewicz, Roman Perez-Soler, Walter R. Perkins, Yiyu Zou, Mary E. Neville, Jin K. Lee, Vladimir Malinin
  • Publication number: 20090130193
    Abstract: One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml.
    Type: Application
    Filed: May 16, 2008
    Publication date: May 21, 2009
    Applicant: Transave, Inc.
    Inventors: Frank G. Pilkiewicz, Roman Perez-Soler, Yiyu Zou, Walter R. Perkins, Jin K. Lee, Vladimir Malinin