Patents by Inventor Roman Z. Sterzycki

Roman Z. Sterzycki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis quaternary MRSA cephem derivatives
    Patent number: 6265394
    Abstract: Provided by the present invention are cephem derivatives represented by the general formula wherein Ar is an optionally substituted lipophilic phenyl, naphthyl or pyridyl group; L1 and L2 are (C1-C6)alkylene optionally substituted with hydroxy or oxo and/or optionally interrupted with a vinylene group, S, O, aryl, heteroaryl, in which R1 is H or (C1-C6)alkyl; A is CO2H, PO3H, SO3H, tetrazolyl or x′{circle around (−)} is a pharmaceutically acceptable anion; and Q is an quaternized nitrogen group. The derivatives are gram-positive antibacterial agents especially useful in the treatment of diseases caused by methicillin-resistant Staphylococcus aureus.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: July 24, 2001
    Assignee: Bristol-Myers Squibb Company
    Inventors: Roman Z. Sterzycki, Oak K. Kim, Yasutsugu Ueda, Stanley V. D'Andrea, Dane M. Springer
  • 2',3'-dideoxy-2'-fluoronucleosides
    Patent number: 5218106
    Abstract: There are disclosed novel 2',3'-dideoxy-2'-fluoronucleosides and 2'-3'-dideoxy-2',3'-didehydro-2'-fluoronucleosides and processes for their preparation. The compounds so produced exhibit therapeutically useful antiviral and, more particularly, anti-HIV effects.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: June 8, 1993
    Assignee: Bristol-Myers Company
    Inventors: Roman Z. Sterzycki, Muzammil M. Mansuri, John C. Martin
  • 2',3'-Dideoxy-2'-fluoronucleosides
    Patent number: 5126506
    Abstract: There are disclosed novel 2',3'-dideoxy-2'-fluoronucleosides and 2'-3'-dideoxy-2',3'-didehydro-2'-fluoronucleosides and processes for their preparation. The compounds so produced exhibit therapeutically useful antiviral and, more particularly, anti-HIV effects.
    Type: Grant
    Filed: September 13, 1990
    Date of Patent: June 30, 1992
    Assignee: Bristol-Myers Company
    Inventors: Roman Z. Sterzycki, Muzammil M. Mansuri, John C. Martin
  • 2',3'-dideoxy-2',3'-didehydro-2'-fluoroarabino-nucleosides
    Patent number: 4973677
    Abstract: There are disclosed novel 2',3'-dideoxy-2'-fluoronucleosides and 2'-3'-dideoxy-2',3'-didehydro-2'-fluoronucleosides and processes for their preparation. The compounds so produced exhibit therapeutically useful antiviral and, more particularly, anti-HIV effects.
    Type: Grant
    Filed: July 11, 1989
    Date of Patent: November 27, 1990
    Assignee: Bristol-Myers Company
    Inventors: Roman Z. Sterzycki, Muzammil M. Mansuri, John C. Martin
  • 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
    Patent number: 4908440
    Abstract: There are disclosed novel 2',3'-dideoxy-2'-fluoronucleosides and 2'-3'-dideoxy-2',3'-didehydro-2'-fluoronucleosides and processes for their preparation. The compounds so produced exhibit therapeutically useful antiviral and, more particularly, anti-HIV effects.
    Type: Grant
    Filed: November 12, 1987
    Date of Patent: March 13, 1990
    Assignee: Bristol Myers Company
    Inventors: Roman Z. Sterzycki, Muzammil M. Mansuri, John C. Martin