Patents by Inventor Romas Alvydas Kudirka

Romas Alvydas Kudirka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrazinyl-Indole Compounds and Methods for Producing a Conjugate
    Publication number: 20230068124
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: July 26, 2022
    Publication date: March 2, 2023
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • Hydrazinyl-indole compounds and methods for producing a conjugate
    Patent number: 11426465
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: August 30, 2022
    Assignee: Redwiid Bioscience, Inc.
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate
    Patent number: 11376334
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: July 5, 2022
    Assignee: R.P. Scherer Technologies, LLC
    Inventors: Stepan Chuprakov, Romas Alvydas Kudirka, Jesse M. McFarland, Albert W. Garafalo, David Rabuka
  • Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate
    Publication number: 20220153696
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: October 8, 2021
    Publication date: May 19, 2022
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof
    Publication number: 20220023440
    Abstract: The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: July 22, 2021
    Publication date: January 27, 2022
    Inventors: David Rabuka, Aaron Edward Albers, Robyn M. Barfield, Gregory W. deHart, Penelope M. Drake, Romas Alvydas Kudirka, Albert W. Garofalo, Jesse M. McFarland
  • Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
    Patent number: 11180451
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: November 23, 2021
    Assignee: Redwood Bioscience, Inc.
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • Anti-HER2 antibody-maytansine conjugates and methods of use thereof
    Patent number: 11097013
    Abstract: The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: August 24, 2021
    Assignee: Redwood Bioscience, Inc.
    Inventors: David Rabuka, Aaron Edward Albers, Robyn M. Barfield, Gregory W. deHart, Penelope M. Drake, Romas Alvydas Kudirka, Albert W. Garofalo, Jesse M. McFarland
  • HYDRAZINYL-INDOLE COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE
    Publication number: 20210162054
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: December 7, 2020
    Publication date: June 3, 2021
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • Hydrazinyl-indole compounds and methods for producing a conjugate
    Patent number: 10888623
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: January 12, 2021
    Assignee: Redwood Bioscience, Inc.
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate
    Publication number: 20200405876
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.
    Type: Application
    Filed: July 22, 2020
    Publication date: December 31, 2020
    Inventors: Stepan Chuprakov, Romas Alvydas Kudirka, Jesse M. McFarland, Albert W. Garafalo, David Rabuka
  • Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate
    Publication number: 20200317610
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: December 20, 2019
    Publication date: October 8, 2020
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate
    Patent number: 10758628
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: September 1, 2020
    Assignee: R.P. Scherer Technologies, LLC
    Inventors: Stepan Chuprakov, Romas Alvydas Kudirka, Jesse M. McFarland, Albert W. Garafalo, David Rabuka
  • Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
    Patent number: 10604483
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: March 31, 2020
    Assignee: Redwood Bioscience, Inc.
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE
    Publication number: 20190389800
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: June 7, 2019
    Publication date: December 26, 2019
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
    Patent number: 10464894
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: November 5, 2019
    Assignee: Redwood Biosciences, Inc.
    Inventors: David Rabuka, Aaron Edward Albers, Romas Alvydas Kudirka, Albert W. Garofalo
  • HYDRAZINYL-INDOLE COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE
    Publication number: 20190314509
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: April 23, 2019
    Publication date: October 17, 2019
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate
    Publication number: 20190192680
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 27, 2019
    Inventors: Stepan Chuprakov, Romas Alvydas Kudirka, Jesse M. McFarland, Albert W. Garafalo, David Rabuka
  • Hydrazinyl-indole compounds and methods for producing a conjugate
    Patent number: 10314919
    Abstract: The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: June 11, 2019
    Assignee: Redwood Bioscience, Inc.
    Inventors: Romas Alvydas Kudirka, Aaron Edward Albers, Robyn M. Barfield, David Rabuka
  • ANTI-HER2 ANTIBODY-MAYTANSINE CONJUGATES AND METHODS OF USE THEREOF
    Publication number: 20190111151
    Abstract: The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
    Type: Application
    Filed: September 26, 2018
    Publication date: April 18, 2019
    Inventors: David Rabuka, Aaron Edward Albers, Robyn M. Barfield, Gregory W. deHart, Penelope M. Drake, Romas Alvydas Kudirka, Albert W. Garofalo, Jesse M. McFarland
  • Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate
    Patent number: 10195283
    Abstract: The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: February 5, 2019
    Assignee: R.P. Scherer Technologies, LLC
    Inventors: Stepan Chuprakov, Romas Alvydas Kudirka, Jesse M. McFarland, Albert W. Garafalo, David Rabuka