Patents by Inventor Romeo A. Rovati

Romeo A. Rovati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5204365
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof ##STR1## where --R.sub.1 is hydrogen or methyl;--X-- is --CO-- or --CH.sub.2 --;--Y-- is >CH--A or its vinylogous group >C.dbd.CH--CH.sub.2 --A, wherein --A is a --NR.sub.4 R.sub.5 group, where each R.sub.4 and R.sub.5, equal or different between them, is C.sub.1 -C.sub.4 -alkyl or a phenyl-substituted C.sub.1 -C.sub.4 -alkyl; or --A is the N-radical of a 5- or 6-membered, uncharged (i.e. neither quaternary nor zwitterionic) monocyclic ring, either aromatic or non-aromatic, said ring containing one N atom, two N atoms, three N atoms or an N/O pair of atoms, all other atoms in the ring being carbon, and said ring being optionally mono- or di-substituted by groups selected from C.sub.1 -C.sub.4 -alkyl, benzyl, 2-furanylmethyl and 2-thienylmethyl;--R.sub.2 is hydrogen or a radical C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, di-(C.sub.1 -C.sub.
    Type: Grant
    Filed: May 24, 1991
    Date of Patent: April 20, 1993
    Assignee: Sociedad Espanola de Especialidades Farmaco-Terapeuticas S.A.
    Inventors: Romeo A. Rovati, Ernesto F. Felip, Ricardo C. Mestres, Eduardo C. Bau
  • Patent number: 5177099
    Abstract: Dichloro-substituted 1-(5H-dibenzo[a,d]cyclohepten-5-yl)-1H-imidazole comnds of formula (I), in which --X-- is either --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--, and their pharmaceutically acceptable addition salts, preferably the nitric acid ones. Products of formula (I) are prepared from products of formula (VI) where Z represents a leaving group such as halogen, by treatment with an excess of imidazole in dimethylformamide. Products (I) show an antifungal activity comparable -or superior- to antimycotics in the market, such as Clotrimazole and Bifonazole.
    Type: Grant
    Filed: May 19, 1992
    Date of Patent: January 5, 1993
    Assignee: Sociedad Espanola de Especialidades Farmaco-Terapeuticas S.A.
    Inventors: Romeo A. Rovati, Ricardo C. Mestres