Patents by Inventor Ron Bihovsky

Ron Bihovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrugs of fencamfamine
    Patent number: 11919836
    Abstract: Disclosed herein are pharmaceutical compositions comprising fencamfamine or fencamfamine related prodrug derivatives for targeted therapeutic applications and methods of synthesizing the compositions.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: March 5, 2024
    Assignee: Praxis Bioresearch, LLC
    Inventors: Sandeep Patil, Ron Bihovsky, Steven A Smith, Yuhua Ji, Valentino Stella, Daniel D. Long, Daniel Marquess
  • Prodrugs of fencamfamine
    Patent number: 11731935
    Abstract: Disclosed herein are pharmaceutical compositions comprising fencamfamine or fencamfamine related prodrug derivatives for targeted therapeutic applications and methods of synthesizing the compositions.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: August 22, 2023
    Assignee: Praxis Bioresearch, LLC
    Inventors: Sandeep Patil, Ron Bihovsky, Steven A Smith, Yuhua Ji, Valentino Stella, Daniel D. Long, Daniel Marquess
  • PRODRUGS OF FENCAMFAMINE
    Publication number: 20200399203
    Abstract: Disclosed herein are pharmaceutical compositions comprising fencamfamine or fencamfamine related prodrug derivatives for targeted therapeutic applications and methods of synthesizing the compositions.
    Type: Application
    Filed: April 14, 2020
    Publication date: December 24, 2020
    Inventors: Sandeep Patil, Ron Bihovsky, Steven A. Smith, Yuhua Ji, Valentino Stella, Daniel D. Long, Daniel Marquess
  • Prodrugs of fencamfamine
    Patent number: 10662146
    Abstract: Disclosed herein are pharmaceutical compositions with fencamfamine or fencamfamine related prodrug derivatives. The pharmaceutical compositions are for targeted therapeutic applications including, but not limited to, treating cancer-related fatigue, apathy in Alzheimer's Disease, major depression, and attention deficit-hyperactivity disorder. Also disclosed are methods of synthesizing the pharmaceutical compositions with fencamfamine or fencamfamine related prodrug derivatives.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: May 26, 2020
    Assignee: PRAXIS BIORESEARCH, LLC
    Inventors: Sandeep Patil, Ron Bihovsky, Steven A. Smith, Yuhua Ji, Valentino Stella, Daniel D. Long, Daniel Marquess
  • PRODRUGS OF FENCAMFAMINE
    Publication number: 20190023650
    Abstract: Disclosed herein are pharmaceutical compositions comprising fencamfamine or fencamfamine related prodrug derivatives for targeted therapeutic applications and methods of synthesizing the compositions.
    Type: Application
    Filed: September 13, 2016
    Publication date: January 24, 2019
    Inventors: Sandeep Patil, Ron Bihovsky, Steven A. Smith, Yuhua JI, Valentino Stella, Daniel D. Long, Daniel Marquess
  • Multicyclic compounds and the use thereof
    Patent number: 7122679
    Abstract: The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: October 17, 2006
    Assignee: Cephalon, Inc.
    Inventors: Mark A. Ator, Ron Bihovsky, Sankar Chatterjee, Derek Dunn, Robert L. Hudkins
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Patent number: 7060683
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: June 13, 2006
    Assignee: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors
    Publication number: 20060069037
    Abstract: This invention relates to peptide-containing ?-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Application
    Filed: November 15, 2005
    Publication date: March 30, 2006
    Applicant: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John Mallamo, Ron Bihovsky, Gregory Wells
  • Peptide-containing ?-ketoamide cysteine and serine protease inhibitors
    Patent number: 7001907
    Abstract: This invention relates to peptide-containing ?-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: February 21, 2006
    Assignee: Cephaon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Publication number: 20040106558
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Application
    Filed: November 20, 2003
    Publication date: June 3, 2004
    Applicant: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors
    Publication number: 20040102609
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Application
    Filed: October 14, 2003
    Publication date: May 27, 2004
    Applicant: Cephalon Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Peptide-containing &agr;-ketoamide cysteine and serine protease inhibitors
    Patent number: 6703368
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: June 12, 2001
    Date of Patent: March 9, 2004
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Patent number: 6686335
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: February 3, 2004
    Assignee: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
    Patent number: 6500802
    Abstract: The present invention is directed to novel peptidyl-2-amino-1-hydroxyalkanesulfonic acid inhibitors of cysteine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: December 31, 2002
    Assignee: Cephalon, Inc.
    Inventors: Ming Tao, Ron Bihovsky
  • Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors
    Publication number: 20020055616
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Application
    Filed: June 12, 2001
    Publication date: May 9, 2002
    Applicant: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Novel multicyclic compounds and the use thereof
    Publication number: 20020028815
    Abstract: The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer.
    Type: Application
    Filed: May 8, 2001
    Publication date: March 7, 2002
    Inventors: Mark A. Ator, Ron Bihovsky, Sankar Chatterjee, Derek Dunn, Robert L. Hudkins
  • Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
    Patent number: 6348448
    Abstract: The present invention is directed to novel peptidyl-2-amino-1-hydroxyalkanesulfonic acid inhibitors of cysteine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: April 15, 1998
    Date of Patent: February 19, 2002
    Assignee: Cephalon, Inc.
    Inventors: Ming Tao, Ron Bihovsky
  • Peptide-containing &agr;-ketoamide cysteine and serine protease inhibitors
    Patent number: 6288231
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: September 11, 2001
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Peptidyl-containing .alpha.-ketoamide cysteine and serine protease inhibitors
    Patent number: 6150378
    Abstract: This invention relates to peptide-containing .alpha.-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: November 21, 2000
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Benzothiazo and related heterocyclic group-containing cysteine and serine protease inhibitors
    Patent number: 5952328
    Abstract: The present invention is directed to novel benzothiazo and related heterocyclic group-containing inhibitors of cysteine or serine proteases. Methods for using the same are also described.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: September 14, 1999
    Assignee: Cephalon, Inc.
    Inventors: Ron Bihovsky, Gregory J. Wells, Ming Tao