Abstract: The present invention involves methods and apparatus for destroying or inactivating pathogens in body cavities or on body surfaces using ultraviolet (UV) light of various wavelengths. More particularly, the invention comprises a portable apparatus containing an energy source, UV light emitter, insertion portion and controller. The energy source may be a battery and some embodiments may include a power converter. The UV emitter may be an LED, excimer lamp, laser, laser diode, fluorescent lamp, xenon flash lamp, arc lamp or gas discharge lamp. The insertion portion may be configured to enter certain body cavities and to transmit the UV light to target areas on body surfaces or within body cavities. The device may also incorporate light filters to block unwanted wavelengths. Some embodiments include a light sensor to detect visible and UV light and may measure the intensity and spectral characteristics of the UV emitter.