Abstract: A method of notifying an owner of a lost item in a vehicle having a vehicle compartment is provided. The method comprises providing at least one sensor to sense the lost item in the vehicle compartment. The method further comprises sensing the lost item on a point relative to a spherical coordinate system to define a sensed item data and determining a position of the lost item in cartesian coordinates based on the sensed item data to define a position data. The method further comprises translating the sensed item data and the position data for visualization of the lost item to define an item image of the lost item relative to the vehicle compartment, and updating an inventory list of lost objects to include the lost item with the item image. The method further comprises identifying the owner of the lost item by way of a perception algorithm, providing notification to the owner of the lost item, and providing viewable access of the item image such that the image is viewed by the owner of the lost item.

Abstract: A method includes a workload management (WLM) server that receives a first CHECK WORKLOAD command for a workload in a queue of the WLM server. It may be determined whether the workload is ready to run on a WLM client. If the workload is not ready to run, a wait time for the workload with the WLM server is dynamically estimated. The wait time is sent to the WLM client. If the workload is ready to run, then a response is sent to the WLM client that workload is ready to run.

Abstract: A method includes a workload management (WLM) server that receives a first CHECK WORKLOAD command for a workload in a queue of the WLM server. It may be determined whether the workload is ready to run on a WLM client. If the workload is not ready to run, a wait time for the workload with the WLM server is dynamically estimated. The wait time is sent to the WLM client. If the workload is ready to run, then a response is sent to the WLM client that workload is ready to run.

Abstract: A method includes a workload management (WLM) server that receives a first CHECK WORKLOAD command for a workload in a queue of the WLM server. It may be determined whether the workload is ready to run on a WLM client. If the workload is not ready to run, a wait time for the workload with the WLM server is dynamically estimated. The wait time is sent to the WLM client. If the workload is ready to run, then a response is sent to the WLM client that workload is ready to run.

Abstract: A method includes a workload management (WLM) server that receives a first CHECK WORKLOAD command for a workload in a queue of the WLM server. It may be determined whether the workload is ready to run on a WLM client. If the workload is not ready to run, a wait time for the workload with the WLM server is dynamically estimated. The wait time is sent to the WLM client. If the workload is ready to run, then a response is sent to the WLM client that workload is ready to run.

Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in one or more non-aqueous and/or water-miscible solvents, or optionally, in a premix of one or more solvents and one or more surfactants.

Abstract: The present invention is directed to a semi-solid formulation comprising a lipid-regulating agent. Said formulation is prepared by solubilizing said lipid-regulating agent in one or more liquid components to form a clear liquid solution, then solidifying said solution by adding one or more solid or semi-solid components to said solution to form a semi-solid formulation. Said formulation can melt or dissolve upon mixing with a bulk aqueous medium. The resulting formulation results in an increase in drug solubility and oral bioavailability, and an improved dissolution rate.

Abstract: The present invention relates to a stabilized self-emulsifying system, comprising a therapeutically effective amount of o-(chloroacetylcarbamoyl)fumigillol, a pharmaceutically acceptable carrier and a stabilizing component, wherein the pharmaceutically acceptable carrier comprises an oily constituent and at least one surfactant. The stabilizing component comprises from about 1% to about 15% water relative to the weight of the self-emulsifying system, an acid, an adsorbent, or a complex-forming agent.

Abstract: The present invention relates to a stabilized self-emulsifying system, comprising a therapeutically effective amount of o-(chloroacetylcarbamoyl)fumigillol, a pharmaceutically acceptable carrier and a stabilizing component, wherein the pharmaceutically acceptable carrier comprises an oily constituent and at least one surfactant. The stabilizing component comprises from about 1% to about 15% water relative to the weight of the self-emulsifying system, an acid, an adsorbent, or a complex-forming agent.

Abstract: The present invention relates to a stabilized self-emulsifying system, comprising a therapeutically effective amount of o-(chloroacetylcarbamoyl)fumigillol, a pharmaceutically acceptable carrier and a stabilizing component, wherein the pharmaceutically acceptable carrier comprises an oily constituent and at least one surfactant. The stabilizing component comprises from about 1% to about 15% water relative to the weight of the self-emulsifying system, an acid, an adsorbent, or a complex-forming agent.

Abstract: The present invention is directed to a semi-solid formulation comprising a lipid-regulating agent. Said formulation is prepared by solubilizing said lipid-regulating agent in one or more liquid components to form a clear liquid solution, then solidifying said solution by adding one or more solid or semi-solid components to said solution to form a semi-solid formulation. Said formulation can melt or dissolve upon mixing with a bulk aqueous medium. The resulting formulation results in an increase in drug solubility and oral bioavailability, and an improved dissolution rate.

Abstract: The present invention is directed to a process for preparing a formulation comprising a lipid-regulating agent dissolved in a supercritical fluid, spraying the solution through a nozzle to form small particles of the lipid-regulating agent, forming a suspension of the particles of said lipid-regulating agent in a liquid, and collecting the particles.

Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in one or more non-aqueous and/or water-miscible solvents, or optionally, in a premix of one or more solvents and one or more surfactants.

Abstract: Liposomal compositions containing green porphyrins as photosensitizers are improved by enhancing the ratio of phospholipid to photosensitizer and by conducting the hydration an sizing of the liposomes in the composition at low temperature.