Patents by Inventor Ron Stubbers

Ron Stubbers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9453200
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: September 27, 2016
    Assignee: INGENERON INCORPORATED
    Inventors: Ron Stubbers, Michael E. Coleman
  • Publication number: 20160272943
    Abstract: A closed system apparatus and method for isolation and recovery of desired cells from body tissue includes a first container for tissue dissociation by subjection to centrifugation over one or more cycles of rotational acceleration and deceleration, a particle filter to filter out non-dissociated tissue while passing desired cells to a second container for separating the desired cells from connective tissue, unwanted material, liquid, and dissociation-aiding reagent(s) by subjection of the second container to combined centrifugal and gravitational forces that also causes concentration and sedimentation of the cells into a pellet for removal through a valve in the bottom of the second container.
    Type: Application
    Filed: December 15, 2015
    Publication date: September 22, 2016
    Inventors: Greg Stone, Ron Stubbers, Michael E. Coleman, Eckhard Alt
  • Publication number: 20150314041
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: November 5, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150307845
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 29, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150299643
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 22, 2015
    Applicant: InGeneron Incorporated
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150093809
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: September 27, 2013
    Publication date: April 2, 2015
    Applicant: InGeneron, Inc.
    Inventors: Eckhard U. Alt, Ron Stubbers, Michael E. Coleman
  • Publication number: 20150056691
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Application
    Filed: August 28, 2014
    Publication date: February 26, 2015
    Inventors: Ron Stubbers, Michael E. Coleman
  • Patent number: 8951513
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: February 10, 2015
    Assignee: Ingeneron Incorporated
    Inventors: Eckhard U. Alt, Michael E. Coleman, Ron Stubbers
  • Publication number: 20150037387
    Abstract: Apparatus and methods are described for generating autologous tissue grafts, the apparatus including a point of care SVF isolation unit that includes a tissue digestion chamber in fluid communication with a lipid separating chamber, whereby SVF cells are isolated without centrifugation; and a cell seeding chamber in fluid communication with the SVF isolation unit, said cell seeding chamber adapted to support a cell scaffold. Methods and materials for cell seeding, including through the provision of micro rough scaffold surfaces, are also provided.
    Type: Application
    Filed: October 20, 2014
    Publication date: February 5, 2015
    Applicants: Board of Regents of the University of Texas System, Ingeneron, Inc.
    Inventors: Michael E. Coleman, Eckhard U. Alt, Ron Stubbers
  • Patent number: 8865199
    Abstract: Apparatus and methods are described for generating autologous tissue grafts, the apparatus including a point of care SVF isolation unit that includes a tissue digestion chamber in fluid communication with a lipid separating chamber, whereby SVF cells are isolated without centrifugation; and a cell seeding chamber in fluid communication with the SVF isolation unit, said cell seeding chamber adapted to support a cell scaffold. Methods and materials for cell seeding, including through the provision of micro rough scaffold surfaces, are also provided.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: October 21, 2014
    Assignees: Ingeneron, Inc., Board of Regents of the University of Texas System
    Inventors: Michael E. Coleman, Eckhard U. Alt, Ron Stubbers
  • Patent number: 8822202
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: September 2, 2014
    Assignee: Ingeneron Incorporated
    Inventors: Ron Stubbers, Michael Coleman
  • Publication number: 20130337551
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Application
    Filed: October 26, 2012
    Publication date: December 19, 2013
    Applicant: InGeneron Inc.
    Inventors: Ron Stubbers, Michael Coleman
  • Publication number: 20130115697
    Abstract: This document describes methods and an apparatus for recovery of cells from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventors: Eckhard U. Alt, Michael E. Coleman, Ron Stubbers
  • Patent number: 8309342
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: November 13, 2012
    Assignee: InGeneron, Inc.
    Inventors: Ron Stubbers, Michael E. Coleman
  • Publication number: 20120195863
    Abstract: This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of acceleration and deceleration are performed.
    Type: Application
    Filed: December 16, 2011
    Publication date: August 2, 2012
    Inventors: Eckhard U. Alt, Michael E. Coleman, Ron Stubbers
  • Publication number: 20100285588
    Abstract: A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form.
    Type: Application
    Filed: December 3, 2008
    Publication date: November 11, 2010
    Applicant: INGENERON, INC.
    Inventors: Ron Stubbers, Michael E. Coleman
  • Publication number: 20100124563
    Abstract: Apparatus and methods are described for generating autologous tissue grafts, the apparatus including a point of care SVF isolation unit that includes a tissue digestion chamber in fluid communication with a lipid separating chamber, whereby SVF cells are isolated without centrifugation; and a cell seeding chamber in fluid communication with the SVF isolation unit, said cell seeding chamber adapted to support a cell scaffold. Methods and materials for cell seeding, including through the provision of micro rough scaffold surfaces, are also provided.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Applicant: InGeneron, Inc.
    Inventors: Michael E. Coleman, Eckhard U. Alt, Ron Stubbers
  • Patent number: 5012808
    Abstract: A pulse generation and tracking system for connection to an object or a subject under treatment therewith, the waveform being a train of repetitive complex pulses each pulse comprising a large amplitude, short duration positive polarity portion and a small amplitude, long duration negative polarity portion, and a zero value portion. The prescribed pulse train for a subject is delivered by a delivery device, which also provides monitoring of the averaged voltage amplitude of the positive portion in terms of either voltage or current value. The impedance of the subject is expected to change over time and cause the individual pulses to vary from predetermined limits. When this occurs, then a subsequent generation of pulses will be changed so that the pulses are again delivered within the predetermined value limits or boundary. Tracking and generation can be operationally crossed, if desired, so that a voltage out of boundary will cause the current of a subsequent pulse to be changed or vice versa.
    Type: Grant
    Filed: October 17, 1988
    Date of Patent: May 7, 1991
    Assignee: Zion Educational Foundation
    Inventors: Ron Stubbers, Chen Chen, Malcolm Skolnick
  • Patent number: 4779044
    Abstract: A regularly repetitive, almost periodic but non-regularly shaped waveform is amplitude sampled at an interval different from that of the waveform under investigation. For a voltage measurement, the positive samples are averaged for a predetermined count number (one set) and the negative samples are likewise averaged. Zero value samples are ignored. The highest absolute value of the two is taken as a meaningful measurement. Alternatively, one of these values can be selected. For a current measurement, a running average for a predetermined number of sets can also be developed. Finally, frequency can be developed by sensing the transitions and operating a counter on/off at the beginning and ending of a waveform cycle. The count of regular interval counts is then multiplied by the interval time to give the period of the waveform. The reciprocal of the period is a measure of the frequency.
    Type: Grant
    Filed: September 8, 1987
    Date of Patent: October 18, 1988
    Assignee: Zion Educational Foundation
    Inventors: Malcolm Skolnick, Ron Stubbers, Chris Hymel, Chen Chen