Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A vermin trap apparatus and method. The trap comprises a movable path between the entrance and the bait, and sensor means adjacent the movable path for detecting vermin presence on the path. When a vermin detection signal is sent to control means, the control means causes a movable clamping member to trap the vermin for electrocution. Also provided are methods of the path to rotate and/or pivot, thereby dislodging the electrocuted vermin and into a containment region. Methods for electrocuting vermin are also disclosed.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: Specific binding members comprising human antibody antigen binding domains specific for human transforming growth factor beta (TGF?) bind specifically isoforms TGF?2 and TGF?1 or both, preferentially compared with TGF?3. Specific binding members may be isolated and utilized in the treatment of disease, particularly fibrotic disease and also immune/inflammatory diseases. Therapeutic utility is demonstrated using in vitro and in vivo models. Full sequence and binding information is provided, including epitope sequence information for particularly advantageous specific binding member which binds the active form of TGF?2, neutralizing its activity, but does not bind the latent member.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A therapeutic arm exercise device which includes a vertical supporting frame for mounting on a vertical wall surface. An upright elongated exercise base board is pivotally secured relative to the frame for selectively positioning and retaining the board at different angles from vertical to less than vertical. An elongated track is provided on the outer surface of the board and a weight slide is slidably received on this track and is provided with a handle whereby a patient may manually slide the slide up and down along the track for rehabilitation exercise. In addition, the vertical position of the device may be adjusted on the wall. Also, the amount of weight for the slide may be adjusted. Indicia is provided on the board adjacent the track for indicating distance that the slide is moved by the patient upwardly along the track and a biofeedback annunciator is also provided to indicate attainment of a goal distance of upward movement along the track by the slide.

Abstract: A pivot mounting apparatus 210 is provided for pivotally mounting to one another the coal nozzle tip 212 and coal nozzle body 214 of a pulverized solid fuel nozzle 208 of a pulverized solid fuel-fired furnace 10. The pivot mounting apparatus 210 includes a latch interconnecting assembly 220 that includes a pin 222 for insertion in a traversing movement through an insertion passage 224 which passes through both the through hole 216 of the coal nozzle tip 212 and the through hole 218 of the coal nozzle body 214 upon the mutually facing positioning of respective sides of the coal nozzle tip 212 and the coal nozzle body 214 with one another with their respective through holes 216, 218 both co-axial with an insertion axis IAX.

Abstract: A web infeed device for rotary printing presses includes a pointed nose piece having concave side portions. The flexible infeed element is received in a guide, and driving elements are provided for driving the infeed element along the guide.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A device for guiding a web includes a frame, a first angle bar angled with respect to the entering web direction and supported by the frame for movement along a first path, the first angle bar having a first and a second side, a second angle bar angled with respect to the entering web direction and supported by the frame for movement along a second path, and a roller for changing a direction of the web between the first angle bar and second angle bar, the roller being moveable along a third path so as to be movable laterally beyond both the first side and second side of the angle bar.

Abstract: A therapeutic arm exercise device which includes a vertical supporting frame for mounting on a vertical wall surface. An upright elongated exercise base board is pivotally secured relative to the frame for selectively positioning and retaining the board at different angles from vertical to less than vertical. An elongated track is provided on the outer surface of the board and a weight slide is slidably received on this track and is provided with a handle whereby a patient may manually slide the slide up and down along the track for rehabilitation exercise. In addition, the vertical position of the device may be adjusted on the wall. Also, the amount of weight for the slide may be adjusted. Indicia is provided on the board adjacent the track for indicating distance that the slide is moved by the patient upwardly along the track and a biofeedback annunciator is also provided to indicate attainment of a goal distance of upward movement along the track by the slide.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A device for guiding a web includes a frame, a first angle bar angled with respect to the entering web direction and supported by the frame for movement along a first path, the first angle bar having a first side and a second side, a second angle bar angled with respect to the entering web direction and supported by the frame for movement along a second path, and a roller for changing a direction of the web between the first angle bar and second angle bar, the roller being movable along a third path so as to be movable laterally beyond both the first side and second side of the first angle bar.

Abstract: A deployable cup holder for use inside a vehicle having a retaining member depending outwardly frown a support member. The support member is adapted to be received within a receiving receptacle and the retaining member is stowed in a receiving area when the cup holder is in a stowed position. The support member travels out of the receptacle and locks into a deployed position. Once in this deployed position the retaining member provides a receiving area for receiving and supporting a beverage container.

Abstract: A device for guiding a travelling web comprises a first movable angle bar and a second movable angle bar located in respective positions in a first operative mode to guide the travelling web from an entering direction to an exiting direction and to define a first print-to-cut registration setting. In a second operative mode the exiting direction of the travelling web is changed and the print-to-cut register is maintained, whereas in a third operative mode the print-to-cut register is changed and the exiting direction is maintained.

Abstract: A web infeed device for rotary printing presses includes a pointed nose piece having concave side portions. The flexible infeed element is received in a guide, and driving elements are provided for driving the infeed element along the guide.

Abstract: A method for adjusting a first force applied to a movable element in a first position of the movable element by a force applying device, the force applying device applying a second force to the movable element in a second position of the movable element. The method includes connecting the movable element and a base element with a scissors-type linkage; mounting the force applying device to the scissors-type linkage at a first mounting point; mounting the force applying device to the base element at a second mounting point; and moving at least one of the first and the second mounting points along a constant force curve, so that the second force remains constant as the first force is adjusted. A device for adjusting a first force applied to a movable element in a first position is also provided.

Abstract: A printing press comprises a cylinder having an outer surface and a plurality of air holes for providing air to the outer surface. A sound-damping material is located on a section of the outer surface and an axially-removable printing sleeve fits over the outer surface. Also disclosed is a method for reducing noise from a printing press comprising the steps of providing air through air holes in a cylinder having a free end to aid in placement or removal of an axially-removable printing sleeve, and providing a sound-damping surface to an outer surface of the cylinder at the free end.