Abstract: An integrated optical transducer for measuring displacement of a diaphragm comprises the diaphragm, a lens element and a substrate body having a waveguide structure and a coupling element. The diaphragm is arranged distant from the substrate body and substantially parallel to a main extension plane of the substrate body. The waveguide structure is configured to guide light from a light source to the coupling element and from the coupling element to a photodetector. The coupling element is configured to couple at least part of the light in the waveguide structure onto a light path between the coupling element and the diaphragm and to couple light reflected by a surface of the diaphragm from the light path into the waveguide structure. The lens element is arranged on the light path such that light on the light path passes through the lens element.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: Co-crystals of itanapraced; methods of preparation of the co-crystals; uses of the co-crystals as APIs; formulations containg the co-crystals; uses of the co-crystals and formulations for prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries; and methods of prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries are described.

Abstract: Co-crystals of itanapraced; methods of preparation of the co-crystals; uses of the co-crystals as APIs; formulations containing the co-crystals; uses of the co-crystals and formulations for prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries; and methods of prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries are described.

Abstract: Co-crystals of itanapraced; methods of preparation of the co-crystals; uses of the co-crystals as APIs; formulations containing the co-crystals; uses of the co-crystals and formulations for prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries; and methods of prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries are described.

Abstract: Co-crystals of itanapraced; methods of preparation of the co-crystals; uses of the co-crystals as APIs; formulations containing the co-crystals; uses of the co-crystals and formulations for prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries; and methods of prevention and treatment of neurodegeneration disorders, infections, dementias, inflammation, and injuries are described.

Abstract: The present disclosure is directed to a crystalline, hydrated form of afatinib dimaleate having about 2 to 3 molecules of water, designated as Form Z, a pharmaceutical composition comprising the form, its method of use for treating a patient, and process for its preparation.

Abstract: The present disclosure is directed to a crystalline, hydrated form of afatinib dimaleate having about 2 to 3 molecules of water, designated as Form Z, a pharmaceutical composition comprising the form, its method of use for treating a patient, and process for its preparation.

Abstract: An improved led fixture apparatus and manufacturing methods thereto is disclosed herein. In preferred embodiments, the apparatus comprises a power supply, a base, a circuit board mounted within the base, a LED connected to the circuit board, and wherein the base is constructed from material comprising forged metal and configured to act as a heat sync. In preferred embodiments, the base is made from forged aluminum alloy anodized for emissivity conduction and comprises a plurality of fins adapted to increase the surface area of the base to improve heat dissipation.

Abstract: An indicator system for a vehicle having an electric motor and a rechargeable battery can include an indicator having a body with a first end and a second opposite end. The body can include an indicator area defining a plurality of contiguous indicator segments therebetween. Each indicator segment can be configured to provide a separate status indication of at least one of a state of charge of the rechargeable battery, a state of a user specified vehicle feature condition, and a fault condition associated with charging of the rechargeable battery. The indicator can be mounted to a vehicle structure about the first end such that the second end extends away from the vehicle structure and the indicator area is externally visible relative to the vehicle from multiple viewpoints beyond a periphery of the vehicle.

Abstract: An indicator system for a vehicle having an electric motor and a rechargeable battery can include an indicator having a body with a first end and a second opposite end. The body can include an indicator area defining a plurality of contiguous indicator segments therebetween. Each indicator segment can be configured to provide a separate status indication of at least one of a state of charge of the rechargeable battery, a state of a user specified vehicle feature condition, and a fault condition associated with charging of the rechargeable battery. The indicator can be mounted to a vehicle structure about the first end such that the second end extends away from the vehicle structure and the indicator area is externally visible relative to the vehicle from multiple viewpoints beyond a periphery of the vehicle.

Abstract: A method for identifying new customers or recently changed telephone services is disclosed. The methodology discovers systems and methods for capturing telephone numbers that appear on the records of recent telephone calls of a communications network, which can or cannot be a network customer, and categorizing the telephone number as a known telephone number or an unknown telephone number. The methodology includes looking-up a name and address for telephone numbers, which are categorized as unknown telephone numbers, in a current directory service. A comparison can be performed using the looked-up name and address from the current directory service with names and addresses in a historical data source. If the looked-up name and address from the current directory service differ from name and address in the historical data source, the unknown telephone number is identified as a new customer or a recently changed telephone service.

Abstract: A disabling module in communication with a control module operates to disable or partially disable equipment in response to the failure of a user to complete a specific task, such as make a loan or lease payment. When a user makes a payment on an outstanding loan, usually a loan related to specific equipment, such as a motorized vehicle, a control module is notified of the payment. The control module causes the equipment to be enabled or disabled in accordance with payment receipt.

Abstract: A disabling module in communication with a control module operates to disable or partially disable equipment in response to the failure of a user to complete a specific task, such as make a loan or lease payment. When a user makes a payment on an outstanding loan, usually a loan related to specific equipment, such as a motorized vehicle, a control module is notified of the payment. The control module causes the equipment to be enabled or disabled in accordance with payment receipt.

Abstract: A mounting method for mounting a plastic panel (12) to a vehicle substrate provides a support flange (24) on an inner surface of the panel. A reference nodule (28) is positioned on the inner surface of the panel. An elongate bracket (14) has an upper edge (34) thereof engaging the support flange (24). The bracket (14) has a reference notch (40) engaging the reference nodule (28) positioning the bracket (14) relative to the panel (12). A plurality of retainers (18) are mounted on the bracket (14). A double-sided adhesive tape (16) has a first adhesive on a first side thereof compatible for adhesion to the bracket (14) and a second adhesive on a second side thereof compatible for adhesion to the panel (12). The first side of the adhesive tape (16) is applied to the bracket (14) and the second side is applied to the panel (12). The tape (16) allows expansion and contraction movement of the panel (12) while securely retaining the panel (12) to the vehicle substrate.

Abstract: A mounting method for mounting a plastic panel (12) to a vehicle substrate provides a support flange (24) on an inner surface of the panel. A reference nodule (28) is positioned on the inner surface of the panel. An elongate bracket (14) has an upper edge (34) thereof engaging the support flange (24). The bracket (14) has a reference notch (40) engaging the reference nodule (28) positioning the bracket (14) relative to the panel (12). A plurality of retainers (18) are mounted on the bracket (14). A double-sided adhesive tape (16) has a first adhesive on a first side thereof compatible for adhesion to the bracket (14) and a second adhesive on a second side thereof compatible for adhesion to the panel (12). The first side of the adhesive tape (16) is applied to the bracket (14) and the second side is applied to the panel (12). The tape (16) allows expansion and contraction movement of the panel (12) while securely retaining the panel (12) to the vehicle substrate.

Abstract: A method is provided for dosing powdered material from a supply container having a vertically suspending discharge tube of an elastically deformable material, by squeezing said discharge tube at locations, which periodically move along a part of the discharge tube length. In this method, the squeezing of the discharge tube is effected in a similar way as the flexible tube of a peristaltic pump of the type, with which the tube engages a support wall on one side and with which a peristaltic mechanism is provided on the opposite side for squeezing the tube according to a travelling wave, the length of which does not exceed one single wave length.

Abstract: A spoiler to rear deck lid assembly that absorbs energy from a rear impact while maintaining the connection of the spoiler to the rear deck lid of a vehicle. The spoiler utilizes rigid fasteners to connect the front portion of the spoiler to the rear deck lid and sliding fasteners to connect the rear portion of the spoiler to the rear deck lid. The rear deck lid also has a structurally weakened portion in the rear centermost portion of the spoiler so as to deform and absorb energy upon an initial impact of a rearward impact. The rear deck lid also has a structurally weakened portion between the rigid fasteners and the sliding fasteners so that the rear deck lid buckles upward from the rearward impact, thus absorbing energy and aiding in disconnecting the rigid fasteners from the rear deck lid.