Abstract: The present invention relates to novel anti-PD1 and anti-LAG3 antibody molecules. The invention also relates to nucleic acids encoding such antibody molecules; to methods for preparing such antibody molecules; to host cells expressing or capable of expressing such antibody molecules; to compositions comprising such antibody molecules; and to uses of such antibody molecules or such compositions, in particular for therapeutic purposes in the field of cancer diseases.

Abstract: Described herein are methods of preparing compounds derived from triglycerides or condensation polymers such as polyesters and/or polyamides. The methods may include subjecting triglyceride or condensation polymer containing matter to mechanical processing in the presence of a nucleophile.

Abstract: Embodiments described herein relate generally to plant extract compositions and methods to isolate cutin-derived monomers, oligomers, and mixtures thereof for application in agricultural coating formulations, and in particular, to methods of preparing plant extract compositions that include functionalized and non-functionalized fatty acids and fatty esters (as well as their oligomers and mixtures thereof), which are substantially free from accompanying plant-derived compounds (e.g., proteins, polysaccharides, phenols, lignans, aromatic acids, terpenoids, flavonoids, carotenoids, alkaloids, alcohols, alkanes, and aldehydes) and can be used in agricultural coating formulations.

Abstract: Dental implant, comprising an external thread arranged on an outside of the dental implant for fastening the dental implant to a jawbone. Further, the implant comprises an opening extending along a longitudinal axis of the dental implant, in which opening an internal thread for fastening a superstructure to the dental implant is arranged. Still further, the implant comprises an interface for fastening the superstructure to the dental implant, which interface is arranged at a front end of the dental implant. The interface is suitable for direct attachment of a superstructure to the dental implant without the use of an abutment.

Abstract: Embodiments described herein relate generally to plant extract compositions and methods to isolate fatty acid esters derived from crosslinked polyesters. Particular embodiments are directed to methods of preparing compositions of fatty acid esters by treating crosslinked polyesters or other crosslinked networks with an acid and an alcohol.

Abstract: Dental implant, comprising an external thread arranged on an outside of the dental implant for fastening the dental implant to a jawbone. Further, the implant comprises an opening extending along a longitudinal axis of the dental implant, in which opening an internal thread for fastening a superstructure to the dental implant is arranged. Still further, the implant comprises an interface for fastening the superstructure to the dental implant, which interface is arranged at a front end of the dental implant. The interface is suitable for direct attachment of a superstructure to the dental implant without the use of an abutment.

Abstract: In one embodiment, an apparatus comprises a processor to: receive a request to configure a secure execution environment for a first workload; configure a first set of secure execution enclaves for execution of the first workload, wherein the first set of secure execution enclaves is configured on a first set of processing resources, wherein the first set of processing resources comprises one or more central processing units and one or more accelerators; configure a first set of secure datapaths for communication among the first set of secure execution enclaves during execution of the first workload, wherein the first set of secure datapaths is configured over a first set of interconnect resources; configure the secure execution environment for the first workload, wherein the secure execution environment comprises the first set of secure execution enclaves and the first set of secure datapaths.

Abstract: An example apparatus includes at least one memory, instructions, and at least one processor to execute the instructions to generate electronic mobile measurement data based on network communications received from first client devices, select attributes associated with the electronic mobile measurement data to include in a model, generate the model based on the attributes and a first portion of the electronic mobile measurement data, determine a percentage of a second portion of the electronic mobile measurement data that the model correctly associates with corresponding first users of the first client devices, and when the percentage satisfies a threshold determine: (a) when a second user operating a second client device is a primary user, and (b) when the user operating the second client device is a third user, and associate demographic information of the second user with the electronic mobile measurement data to reduce a misattribution error.

Abstract: Methods and apparatus to compensate impression data for misattribution and non-coverage are disclosed.

Abstract: An example apparatus includes at least one memory, instructions, and at least one processor to execute the instructions to generate electronic mobile measurement data based on network communications received from first client devices, select attributes associated with the electronic mobile measurement data to include in a model, generate the model based on the attributes and a first portion of the electronic mobile measurement data, determine a percentage of a second portion of the electronic mobile measurement data that the model correctly associates with corresponding first users of the first client devices, and when the percentage satisfies a threshold determine: (a) when a second user operating a second client device is a primary user, and (b) when the user operating the second client device is a third user, and associate demographic information of the second user with the electronic mobile measurement data to reduce a misattribution error.

Abstract: An example apparatus includes at least one memory, instructions in the apparatus, and processor circuitry to execute the instructions to access first cookies and a plurality of user identifiers, the first cookies and the user identifiers corresponding to devices accessing media, determine an error between a first demographic estimate based on the first cookies forming a pattern and based on a second demographic estimate corresponding to the user identifiers, obtain impression information from a database proprietor, the impression information including second cookies, identify a subset of the second cookies that are associated with a same person based on the pattern, and associate impressions corresponding to the subset with the same person.

Abstract: Examples apparatus disclosed herein are to determine a plurality of weights based on a data structure having elements corresponding to pairings of ones of a plurality of demographic partition statistics and ones of a plurality of baseline demographic statistics obtained for a target population, the demographic partition statistics corresponding to a plurality of demographic partitions of a sample population, a first element of the data structure to combine a first one of the demographic partition statistics with a first one of the baseline demographic statistics of the target population based on a first value corresponding to a numerator term of an expression and a second value corresponding to a denominator term of the expression, the weights corresponding respectively to the demographic partitions of the sample population. Disclosed example apparatus are also to adjust the attribute data based on the weights to determine ratings data for the target population.

Abstract: Methods and apparatus to adjust media impressions based on media impression notification loss rates in network communications are disclosed.

Abstract: A secret key value that is inaccessible to software is scrambled according to registers consisting of one-time programmable (OTP) bits. A first OTP register is used to change the scrambling of the secret key value whenever a lifecycle event occurs. A second OTP register is used to undo the change in the scrambling of the secret key. A third OTP register is used to affect a permanent change to the scrambling of the secret key. The scrambled values of the secret key (whether changed or unchanged) are used as seeds to produce keys for cryptographic operations by a device.

Abstract: Methods and apparatus to compensate impression data for misattribution and non-coverage are disclosed.

Abstract: Methods and apparatus to adjust media impressions based on media impression notification loss rates in network communications are disclosed.

Abstract: A host Virtual Machine Monitor (VMM) operates “blindly,” without the host VMM having the ability to access data within a guest virtual machine (VM) or the ability to access directly control structures that control execution flow of the guest VM. Guest VMs execute within a protected region of memory (called a key domain) that even the host VMM cannot access. Virtualization data structures that pertain to the execution state (e.g., a Virtual Machine Control Structure (VMCS)) and memory mappings (e.g., Extended Page Tables (EPTs)) of the guest VM are also located in the protected memory region and are also encrypted with the key domain key. The host VMM and other guest VMs, which do not possess the key domain key for other key domains, cannot directly modify these control structures nor access the protected memory region. The host VMM, however, using VMPageIn and VMPageOut instructions, can build virtual machines in key domains and page VM pages in and out of key domains.

Abstract: This invention relates to pharmaceutical compositions and methods for treating (including managing) or preventing metabolic syndrome related conditions using one or more RAR? (e.g., RAR?2) agonists. Such conditions include, but are not limited to, diseases in pancreas, liver, kidney, testes, muscle, or adipose tissue, as well as other organs that are associated with high fat diet and/or vitamin A deficiency, as well as other conditions associated with abnormal level of triglyceride, cholesterol and/or glucose.

Abstract: A write request causes controller circuitry to write an encrypted data line and First Tier metadata portion including MAC data and a first portion of ECC data to a first memory circuitry portion and a second portion of ECC data to a sequestered, second memory circuitry portion. A read request causes the controller circuitry to read the encrypted data line and the First Tier metadata portion from the first memory circuitry portion. Using the first portion of the ECC data included in the First Tier metadata portion, the controller circuitry determines if an error exists in the encrypted data line. If no error is detected, the controller circuitry decrypts and verifies the data line using the MAC data included in the First Tier metadata portion. If an error in the data line is detected by the controller circuitry, the Second Tier metadata portion, containing the second portion of the ECC data is fetched from the sequestered, second memory circuitry portion and the error corrected.

Abstract: An example apparatus includes at least one memory, instructions in the apparatus, and processor circuitry to execute the instructions to access first cookies and a plurality of user identifiers, the first cookies and the user identifiers corresponding to devices accessing media, determine an error between a first demographic estimate based on the first cookies forming a pattern and based on a second demographic estimate corresponding to the user identifiers, obtain impression information from a database proprietor, the impression information including second cookies, identify a subset of the second cookies that are associated with a same person based on the pattern, and associate impressions corresponding to the subset with the same person.