Patents by Inventor Ronald A. Wohl

Ronald A. Wohl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]-1H-benzimidazole-1-butanamine and use thereof as a cardiotonic agent
    Patent number: 4517310
    Abstract: The compound N-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]-1H-benzimidazole-1-butanamine and methods for its manufacture and use are described herein. The compound is a cardiotonic agent useful primarily in the treatment of congestive heart failure.
    Type: Grant
    Filed: July 28, 1981
    Date of Patent: May 14, 1985
    Assignee: Berlex Laboratories, Inc.
    Inventors: Julius Diamond, Ronald A. Wohl
  • Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
    Patent number: 4434174
    Abstract: 3-Phenoxy-2-hydroxypropylamines having an N-benzimidazolyalkyl substituent and similar compounds are described herein. They are obtained by the reaction of the appropriate imidazole-1-alkanamine with an epoxide, and they are useful primarily as .beta..sub.1 -agonists/.beta.-sympathomimetic agents.
    Type: Grant
    Filed: March 2, 1982
    Date of Patent: February 28, 1984
    Assignee: Berlex Laboratories, Inc.
    Inventors: Julius Diamond, Ronald A. Wohl
  • Method of use of antiarrhythmic 1-arylcarbamoylalkyl imidazole derivatives, composition
    Patent number: 4415587
    Abstract: Novel 1,2-disubstituted imidazol(in)es are described herein. The compounds are generally produced by reacting a haloacylanilide with an excess of 2-substituted-imidazol(in)e. The compounds are antiarrhythmic agents.
    Type: Grant
    Filed: August 12, 1982
    Date of Patent: November 15, 1983
    Assignee: Berlex Laboratories, Inc.
    Inventors: Julius Diamond, Thomas K. Morgan, Jr., Ronald A. Wohl
  • N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
    Patent number: 4363808
    Abstract: 3-Phenoxy-2-hydroxypropylamines having an N-benzimidazolyalkyl substituent and similar compounds are described herein. They are obtained by the reaction of the appropriate imidazole-1-alkanamine with an epoxide, and they are useful primarily as .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: May 7, 1981
    Date of Patent: December 14, 1982
    Assignee: Berlex Laboratories, Inc.
    Inventors: Julius Diamond, Ronald A. Wohl
  • Antiarrythmic 1-arylcarbamoylalkyl-2-imidazoline derivatives, composition and method of use
    Patent number: 4353921
    Abstract: Novel 1,2-disubstituted imidazol(in)es are described herein. The compounds are generally produced by reacting a haloacylanilide with an excess of 2-substituted-imidazol(in)e. The compounds are antiarrhythmic agents.
    Type: Grant
    Filed: June 19, 1981
    Date of Patent: October 12, 1982
    Assignee: Berlex Laboratories, Inc.
    Inventors: Julius Diamond, Thomas K. Morgan, Jr., Ronald A. Wohl
  • Process for preparing substituted bis(amidinoureas)
    Patent number: 4209624
    Abstract: A process is disclosed for preparing substituted bis-(amidinoureas) by reacting a 1-substituted-4-alkyl-4-isothiobiuret with a compound containing two aliphatic amino groups.
    Type: Grant
    Filed: July 19, 1977
    Date of Patent: June 24, 1980
    Assignee: Cooper Laboratories, Inc.
    Inventor: Ronald A. Wohl
  • Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines
    Patent number: 4169106
    Abstract: Novel N,N'-bis(phenylcarbamoylalkyl)amidines having antiarrhythmic activity are disclosed. They are prepared by reacting an aminoalkanoylanilide with an active acid derivative such as an imidic acid ester or an alkyl orthoester.
    Type: Grant
    Filed: November 8, 1978
    Date of Patent: September 25, 1979
    Assignee: Cooper Laboratories, Inc.
    Inventors: Julius Diamond, Ronald A. Wohl
  • 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds
    Patent number: 4139537
    Abstract: Cardiac arrhythmias can be treated by administering an effective amount of 3-aryloxy-1-(2-or 4-iminodihydro-1-pyridyl)-2-propanol or phamaceutically acceptable acid addition compound. Many new effective compounds of this type are disclosed.
    Type: Grant
    Filed: June 29, 1976
    Date of Patent: February 13, 1979
    Assignee: Cooper Laboratories, Inc.
    Inventors: Julius Diamond, Ronald A. Wohl