Patents by Inventor Ronald Aungst
Ronald Aungst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9963427Abstract: Provided are dithiol mucolytic agents. These agents increase the liquefaction of mucus in a patient with excessive mucus or mucus with increased viscoelastic, cohesive, or adhesive properties. Also provided are a variety of methods of treatment using these inventive mucolytic agents.Type: GrantFiled: March 11, 2016Date of Patent: May 8, 2018Assignee: PARION SCIENCES, INC.Inventors: Michael R. Johnson, William R. Thelin, Ronald A. Aungst, Jr.
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Publication number: 20160194278Abstract: Provided are dithiol mucolytic agents. These agents increase the liquefaction of mucus in a patient with excessive mucus or mucus with increased viscoelastic, cohesive, or adhesive properties. Also provided are a variety of methods of treatment using these inventive mucolytic agents.Type: ApplicationFiled: March 11, 2016Publication date: July 7, 2016Applicant: PARION SCIENCES, INC.Inventors: Michael R. JOHNSON, William R. THELIN, Ronald A. AUNGST, JR.
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Patent number: 9346753Abstract: Provided are dithiol mucolytic agents. These agents increase the liquefaction of mucus in a patient with excessive mucus or mucus with increased viscoelastic, cohesive, or adhesive properties. Also provided are a variety of methods of treatment using these inventive mucolytic agents.Type: GrantFiled: August 13, 2014Date of Patent: May 24, 2016Assignee: PARION SCIENCES, INC.Inventors: Michael R. Johnson, William R. Thelin, Ronald A. Aungst, Jr.
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Publication number: 20150056305Abstract: Provided are dithiol mucolytic agents. These agents increase the liquefaction of mucus in a patient with excessive mucus or mucus with increased viscoelastic, cohesive, or adhesive properties. Also provided are a variety of methods of treatment using these inventive mucolytic agents.Type: ApplicationFiled: August 13, 2014Publication date: February 26, 2015Applicant: PARION SCIENCES, INC.Inventors: Michael R. Johnson, William R. Thelin, Ronald A. Aungst, JR.
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Patent number: 7592332Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: GrantFiled: August 29, 2008Date of Patent: September 22, 2009Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Daniel R. Goldberg, Ming-Hong Hao, Zhaoming Xiong, Ronald A. Aungst, Amy L. Davis
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Patent number: 7511042Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: GrantFiled: December 1, 2004Date of Patent: March 31, 2009Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Daniel R. Goldberg, Abdelhakim Hammach, Matthew Russell Netherton, Ronald A. Aungst
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Patent number: 7485657Abstract: Disclosed are compounds of formula (I) The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and the pharmaceutical compositions comprising these compounds.Type: GrantFiled: May 3, 2005Date of Patent: February 3, 2009Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Ming-Hong Hao, Alan David Swinamer, Ronald A. Aungst
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Publication number: 20090023701Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: August 29, 2008Publication date: January 22, 2009Inventors: Ronald A. Aungst, Derek Cogan, Amy L. Davis, Daniel R. Goldberg, Ming-Hong Hao, Zhaoming Xiong
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Patent number: 7335657Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: GrantFiled: June 27, 2006Date of Patent: February 26, 2008Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Pier Francesco Cirillo, Donghong Amy Gao, Daniel R. Goldberg, Abdelhakim Hammach, Ming-Hong Hao, Victor Marc Kamhi, Neil Moss, Matthew Russell Netherton, Kevin Chungeng Qian, Mark Stephen Ralph, Lifen Wu, Zhaoming Xiong, Ronald A. Aungst, Jr.
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Publication number: 20070275946Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: August 15, 2007Publication date: November 29, 2007Inventors: Ronald Aungst, Derek Cogan, Amy Davis, Daniel Goldberg, Ming-Hong Hao, Zhaoming Xiong
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Patent number: 7285545Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: GrantFiled: April 29, 2005Date of Patent: October 23, 2007Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Daniel R. Goldberg, Ming-Hong Hao, Zhaoming Xiong, Ronald A. Aungst, Amy L. Davis
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Publication number: 20060235017Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: June 27, 2006Publication date: October 19, 2006Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Pier Cirillo, Donghong Gao, Daniel Goldberg, Abdelhakim Hammach, Ming-Hong Hao, Victor Kamhi, Neil Moss, Matthew Netherton, Kevin Qian, Mark Ralph, Lifen Wu, Zhaoming Xiong, Ronald Aungst
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Patent number: 7078419Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: GrantFiled: February 27, 2004Date of Patent: July 18, 2006Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Pier Francesco Cirillo, Donghong Amy Gao, Daniel R. Goldberg, Abdelhakim Hammach, Ming-Hong Hao, Victor Marc Kamhi, Neil Moss, Matthew Russell Netherton, Kevin Chungeng Qian, Mark Stephen Ralph, Lifen Wu, Zhaoming Xiong, Ronald A. Aungst, Jr.
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Publication number: 20050256113Abstract: Disclosed are compounds of formula (I) The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and the pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: May 3, 2005Publication date: November 17, 2005Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Ming-Hong Hao, Alan Swinamer, Ronald Aungst
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Publication number: 20050245536Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: April 29, 2005Publication date: November 3, 2005Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Ming-Hong Hao, Zhaoming Xiong, Ronald Aungst, Amy Davis, Derek Cogan, Daniel Goldberg
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Publication number: 20050153972Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.Type: ApplicationFiled: December 1, 2004Publication date: July 14, 2005Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Derek Cogan, Daniel Goldberg, Abdelhakim Hammach, Matthew Netherton, Ronald Aungst