Patents by Inventor Ronald B. Rowley

Ronald B. Rowley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic non-human mammals expressing constitutively activated tyrosine kinase receptors
    Patent number: 7265260
    Abstract: A transgenic non-human mammal whose germ cells and somatic cells contain a constructively activated tyrosine kinase receptor introduced into the mammal, or an ancestor of the mammal, at an embryonic stage. The transgenic non-human mammals can be used as ligand-independent in vivo models for the identification and development of selective tyrosine kinase modulators for the treatment of cancer.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: September 4, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: David K. Bol, Joan M. Carboni, Ronald B. Rowley, Tai W. Wong, Francis Y. Lee
  • Transgenic non-human mammals expressing constitutively activated tyrosine kinase receptors
    Publication number: 20030182668
    Abstract: A transgenic non-human mammal whose germ cells and somatic cells contain a constitutively activated tyrosine kinase receptor introduced into the mammal, or an ancestor of the mammal, at an embryonic stage. The transgenic non-human mammals can be used as ligand-independent in vivo models for the identification and development of selective tyrosine kinase modulators for the treatment of cancer.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 25, 2003
    Inventors: David K. Bol, Joan M. Carboni, Ronald B. Rowley, Tai W. Wong, Francis Y. Lee