Patents by Inventor Ronald Bowditch

Ronald Bowditch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides for promoting cell attachment
    Patent number: 6316412
    Abstract: Novel polypeptides derived from human fibronectin are described which bind to integrin receptors expressed by cells. The receptor binding site of human fibronectin begins at amino acid residue 1394 and ends at residue 1400 of fibronectin. The polypeptides facilitate attachment of cells to substrates either alone or in conjunction with RGD-containing peptides. Vectors, fusion proteins and antibodies are also described. Methods for promoting cell attachment and for inhibiting cell adhesion are also described.
    Type: Grant
    Filed: December 1, 1998
    Date of Patent: November 13, 2001
    Assignee: The Scripps Research Institute
    Inventors: Mark H. Ginsberg, Edward F. Plow, Ronald Bowditch
  • Polypeptides for promoting cell attachment
    Patent number: 5843774
    Abstract: Novel polypeptides derived from human fibronectin are described which bind to integrin receptors expressed by cells. The receptor binding site of human fibronectin begins at amino acid residue 1394 and ends at residue 1400 of fibronectin. The polypeptides facilitate attachment of cells to substrates either alone or in conjunction with RGD-containing peptides. Vectors, fusion proteins and antibodies are also described. Methods for promoting cell attachment and for inhibiting cell adhesion are also described.
    Type: Grant
    Filed: February 25, 1997
    Date of Patent: December 1, 1998
    Assignee: The Scripps Research Institute
    Inventors: Mark H. Ginsberg, Edward F. Plow, Ronald Bowditch
  • Polypeptides for promoting cell attachment
    Patent number: 5773574
    Abstract: Novel polypeptides derived from human fibronectin are described which bind to integrin receptors expressed by cells. The receptor binding site of human fibronectin begins at amino acid residue 1394 and ends at residue 1400 of fibronectin. The polypeptides facilitate attachment of cells to substrates either alone or in conjunction with RGD-containing peptides. Vectors, fusion proteins and antibodies are also described. Methods for promoting cell attachment and for inhibiting cell adhesion are also described.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: June 30, 1998
    Assignee: The Scripps Research Institute
    Inventors: Mark H. Ginsberg, Edward F. Plow, Ronald Bowditch
  • Polypeptides for promoting cell attachment
    Patent number: 5492890
    Abstract: Novel polypeptides derived from human fibronectin, and fusion proteins containing those peptide sequences are described which define a receptor binding site on fibronectin that binds to the platelet receptor glycoprotein GPIIb-IIIa expressed by cells. The receptor binding site of human fibronectin includes at least fibronectin amino acid residues 1410-1436. The polypeptides facilitate attachment of cells to substrates either alone or in conjunction with RGD-containing peptides. Vectors preparing the fusion proteins and antibodies are also described. Methods for promoting cell attachment and for inhibiting cell adhesion are also described.
    Type: Grant
    Filed: December 5, 1991
    Date of Patent: February 20, 1996
    Assignee: The Scripps Research Institute
    Inventors: Mark H. Ginsberg, Edward F. Plow, Ronald Bowditch