Abstract: Described herein are interleukin-18 receptor binding moieties and uses thereof. An interleukin-18 receptor binding moiety can be an interleukin-18 receptor agonist or antagonist. An interleukin-18 receptor agonist can be an interleukin-18 receptor alpha binding moiety, an interleukin-18 receptor beta binding moiety, or can include interleukin-18 receptor alpha binding moiety and an interleukin-18 receptor beta binding moiety. An interleukin-18 receptor antagonist can be an interleukin-18 receptor alpha binding moiety, an interleukin-18 receptor beta binding moiety, or can include interleukin-18 receptor alpha binding moiety and an interleukin-18 receptor beta binding moiety. Interleukin-18 receptor agonists and interleukin-18 receptor antagonists can be formulated in a pharmaceutical formulation.

Abstract: IL-7R??c binding compounds and pharmaceutical compositions comprising the IL-7R??c binding compounds are disclosed. IL-7R??c bonding compounds can act as IL-7R agonists and are useful in treating cancer, viral diseases, autoimmune diseases, and inflammatory diseases.

Abstract: The use of IL-7R??c agonist peptides in cell manufacturing is disclosed. The IL-7R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-7R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: The use of IL-2R??c agonist peptides in cell manufacturing is disclosed. The IL-2R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-2R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: A system and method for monitoring the quality of signals transmitted to a remote service area that is located outside of the broadcast area of a main broadcast site. The present invention converts and combines the signals that are to be broadcast from the main broadcast site to a satellite for redistribution to the remote service areas. The converted and combined signals are looped back to a network monitoring operations located at the main broadcast site before being transmitted to the satellite. In another embodiment, the remote broadcast sites send signal strength measurements to the network monitoring operations to provide an indication of satellite transmission problems not related to the quality of the signal being broadcast from the main broadcast site.

Abstract: A system and method for monitoring the quality of signals transmitted to a remote service area that is located outside of the broadcast area of a main broadcast site. The present invention converts and combines the signals that are to be broadcast from the main broadcast site to a satellite for redistribution to the remote service areas. The converted and combined signals are looped back to a network monitoring operations located at the main broadcast site before being transmitted to the satellite. In another embodiment, the remote broadcast sites send signal strength measurements to the network monitoring operations to provide an indication of satellite transmission problems not related to the quality of the signal being broadcast from the main broadcast site.