Patents by Inventor Ronald Carrasquillo

Ronald Carrasquillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR SYNTHESIZING CATIONIC LIPIDS
    Publication number: 20230265050
    Abstract: The present application provides processes for synthesizing cationic lipids of Formula I useful in the synthesis of fat-soluble compositions for targeting and enhancing activity of therapeutic molecules, including siRNA.
    Type: Application
    Filed: June 22, 2021
    Publication date: August 24, 2023
    Inventors: Gregory Louis Beutner, Ronald Carrasquillo-Flores, Federico Lora Gonzalez, Michael J. Smith
  • PROCESS FOR SYNTHESIZING TARGETING MOLECULES
    Publication number: 20230250053
    Abstract: The present application provides processes for synthesizing targeting molecules of Formula (I) comprising a retinoid moiety useful in the synthesis of fat-soluble compounds for targeting and enhancing activity of therapeutic molecules, including siRNA.
    Type: Application
    Filed: June 22, 2021
    Publication date: August 10, 2023
    Inventors: Zhongping Shi, Yichen Tan, Federico Lora Gonzalez, Ronald Carrasquillo-Flores, Michael J. Smith
  • Process for preparing tetrahydrocarbazole carboxamide compound
    Patent number: 11591314
    Abstract: Disclosed is a process for preparing Compound 8: comprising the step of reacting Compound of 7: wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the intermediates.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: February 28, 2023
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ronald Carrasquillo, Peng Geng, Eric C. Huang, Kishta Katipally, Andrew Lee, Boguslaw Mudryk, Xinhua Qian, Thomas M. Razler, Jianji Wang, Carolyn S. Wei, Steven R. Wisniewski, Ye Zhu
  • PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND
    Publication number: 20210078980
    Abstract: Disclosed is a process for preparing Compound 8: comprising the step of reacting Compound of 7: wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the intermediates.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 18, 2021
    Inventors: Ronald Carrasquillo, Peng Geng, Eric C. Huang, Kishta Katipally, Andrew Lee, Boguslaw Mudryk, Xinhua Qian, Thomas M. Razler, Jianji Wang, Carolyn S. Wei, Steven R. Wisniewski, Ye Zhu
  • Process for preparing tetrahydrocarbazole carboxamide compound
    Patent number: 10875843
    Abstract: Disclosed is a process for preparing Compound 8: (8) comprising the step of reacting Compound of 7: (7) wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the intermediates.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: December 29, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ronald Carrasquillo, Peng Geng, Eric C. Huang, Kishta Katipally, Andrew Lee, Boguslaw Mudryk, Xinhua Qian, Thomas M. Razler, Jianji Wang, Carolyn S. Wei, Steven R. Wisniewski, Ye Zhu
  • PROCESS FOR PREPARING TETRAHYDROCARBAZOLE CARBOXAMIDE COMPOUND
    Publication number: 20200109133
    Abstract: Disclosed is a process for preparing Compound 8: (8) comprising the step of reacting Compound of 7: (7) wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the intermediates.
    Type: Application
    Filed: December 19, 2017
    Publication date: April 9, 2020
    Inventors: Ronald Carrasquillo, Peng Geng, Eric C. Huang, Kishta Katipally, Andrew Lee, Boguslaw M. Mudryk, Xinhua Qian, Thomas M. Razler, Jianji Wang, Carolyn S. Wei, Steven R. Wisniewski, Ye Zhu