Patents by Inventor Ronald Charles Herman

Ronald Charles Herman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloned tetrodotoxin-sensitive sodium channel &agr;-subunit and a splice variant thereof
    Patent number: 6335172
    Abstract: DNA encoding for a voltage-gated, TTX-sensitive sodium channel is isolated. Also disclosed are polypeptide products of recombinant expression of these DNA sequences, expression vectors comprising the DNA sequences, and host cells transformed with these expression vectors. Other aspects of this invention are peptides whose sequences are based on the amino acid sequences deduced from these DNA sequences, antibodies specific for such proteins and peptides, procedures for detection and quantitation of such proteins, and nucleic acids related thereto. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-sensitive sodium channel as a therapeutic target for compounds.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: January 1, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Stephen Gregory Delgado, Paul Shartzer Dietrich, Linda Marie Fish, Ronald Charles Herman, Lakshmi Sangameswaran
  • Cloned tetrodotoxin-sensitive sodium channel .alpha.-subunit and a splice variant thereof
    Patent number: 6030810
    Abstract: DNA encoding for a voltage-gated, TTX-sensitive sodium channel is isolated. Also disclosed are polypeptide products of recombinant expression of these DNA sequences, expression vectors comprising the DNA sequences, and host cells transformed with these expression vectors. Other aspects of this invention are peptides whose sequences are based on the amino acid sequences deduced from these DNA sequences, antibodies specific for such proteins and peptides, procedures for detection and quantitation of such proteins, and nucleic acids related thereto. Another aspect of this invention is the use of this voltage-gated, tetrodotoxin-sensitive sodium channel as a therapeutic target for compounds.
    Type: Grant
    Filed: February 16, 1998
    Date of Patent: February 29, 2000
    Inventors: Stephen Gregory Delgado, Paul Shartzer Dietrich, Linda Marie Fish, Ronald Charles Herman, Lakshmi Sangameswaran