Abstract: A filter assembly for a clean room and a total clean room assembly incorporating the filter assembly wherein the filter assembly includes a filter housing for receiving a suitable filter unit. The filter design of the filter assembly produces a seal between the filter housing and the upper and lower edges of the filter unit to prevent unfiltered air from leaking around the filter housing into the clean room. The filter assembly is also designed to be positively clamped and sealed to a supporting framework, or lattice, in order to provide a totally sealed air delivery system for a clean room.