Patents by Inventor Ronald D. Lewis, II

Ronald D. Lewis, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND INTERMEDIATES FOR THE PREPARATION OF BILE ACID DERIVATIVES
    Publication number: 20220127302
    Abstract: The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof.
    Type: Application
    Filed: June 8, 2021
    Publication date: April 28, 2022
    Inventors: Roberto PELLICCIARI, Antimo GIOIELLO, Gabriel GALVIN, Ronald D. LEWIS, II, Mathew YANIK, Myoung Goo KIM, Frederik Ronald LEUSINK, Bartjan KONING, Thomas HENSEL
  • Methods and intermediates for the preparation of bile acid derivatives
    Patent number: 11066437
    Abstract: The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof, comprising the step of reacting a compound of formula I-4 with a halogenating reagent to provide a compound of formula I-5a
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: July 20, 2021
    Assignee: Intercept Pharmaceuticals, Inc.
    Inventors: Roberto Pellicciari, Antimo Gioiello, Gabriel Galvin, Ronald D. Lewis, II, Mathew Yanik, Myoung Goo Kim, Frederik Ronald Leusink, Bartjan Koning, Thomas Hensel
  • Plasminogen activator inhibitor antagonists
    Patent number: 6677473
    Abstract: Compounds and pharmaceutical compositions useful as plasminogen activator inhibitor (PAI) antagonists are provided. In particular, methods of antagonizing PAI with substituted and unsubstituted aryl and heteroaryl ethers and thioethers, benzils, benzyl ethers, benzoate esters, sulfones and benzophenones are provided.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: January 13, 2004
    Assignee: Corvas International INC
    Inventors: Edwin L. Madison, Terence K. Brunck, Joseph Edward Semple, Marguerita Lim-Wilby, Kent E. Pryor, Ronald D. Lewis, II, David F. Duncan, C. Maxwell Lawrence