Patents by Inventor Ronald D. Snyder

Ronald D. Snyder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyamine derivatives as radioprotective agents
    Patent number: 6114394
    Abstract: The present invention relates to polyamine derivatives of the formula RHN-(CH.sub.2).sub.m -NH-(CH.sub.2).sub.n -NHR wherein m is an integer from 2 to 4, n is an integer from 3 to 10 and R is C.sub.2 -C.sub.6 alkyl or --(CH.sub.2).sub.p -Ar wherein Ar is phenyl or naphthyl and p is an integer from 0 to 2; and the pharmaceutically acceptable addition salts thereof which are useful as radioprotective agents. It relates also to the use of polyamines of the formula RHN-(CH.sub.2).sub.m -NH-(CH.sub.2).sub.n -NH-(CH.sub.2).sub.m -NHR wherein m is an integer from 2 to 4, n is an integer from 3 to 10 and R is C.sub.2 -C.sub.6 alkyl or --(CH.sub.2).sub.p -Ar wherein Ar is phenyl or naphthyl and p is an integer from 0 to 2; and the pharmaceutically acceptable addition salts thereof as radioprotective agents.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: September 5, 2000
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Michael L. Edwards, Ronald D. Snyder
  • Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy
    Patent number: 5595979
    Abstract: The present invention relates to a method of treating a patient afflicted with a neoplastic disease state comprising the administration thereto of an effective antineoplastic amount of ionizing or nonionizing radiation, or an effective antineoplastic amount of a DNA-reactive chemotherapeutic agent in conjunctive therapy with an effective sensitizing amount of a compound of formula (I).
    Type: Grant
    Filed: June 27, 1995
    Date of Patent: January 21, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventor: Ronald D. Snyder
  • N-alkythio polyamine derivatives as radioprotective agents
    Patent number: 5434145
    Abstract: The present invention relates to certain polyamine thiols which are useful as radioprotective agents.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: July 18, 1995
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael L. Edwards, Ronald D. Snyder
  • Polyamine phenols as radioprotective agents
    Patent number: 5354782
    Abstract: The present invention relates to certain polyamine phenols which are useful as radioprotective agents.
    Type: Grant
    Filed: August 30, 1993
    Date of Patent: October 11, 1994
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael L. Edwards, Ronald D. Snyder
  • Polyamine thiols as radioprotective agents
    Patent number: 5217964
    Abstract: The present invention relates to certain polyamine thiols which are useful as radioprotective agents.
    Type: Grant
    Filed: January 23, 1991
    Date of Patent: June 8, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael L. Edwards, Ronald D. Snyder