Patents by Inventor Ronald De Groot

Ronald De Groot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9549974
    Abstract: The invention relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in particular, the invention relates to means and methods to identify, select and isolate a vaccine component for passive and/or active immunization against a microorganism that can be killed by opsonophagocytic cells. The invention relates to a method to identify an opsonophagocytosis inducing antigen as a vaccine component for immunization against a microorganism. The invention describes three pneumococcal proteins SlrA, IgA1 proteinase, and PsaA, and their use as a vaccine component with or without PpmA. The invention also discloses the use of antibodies against said proteins for passive immunization and diagnosis.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: January 24, 2017
    Assignee: MUCOSIS B.V.
    Inventors: Cornelis Johannes Leenhouts, Ronald de Groot, Peter Wilhelmus Maria Hermans
  • Publication number: 20120301501
    Abstract: The invention relates to the field of biology, more specifically to the field of immunology and microbiology. The invention further relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in particular, the invention relates to means and methods to identify, select and isolate a vaccine component for passive and/or active immunisation against a microorganism that can be killed by opsonophagocytic cells. The invention relates to a method to identify an opsonophagocytosis inducing antigen as a vaccine component for immunisation against a microorganism. The invention describes three pneumococcal proteins SlrA, IgA1 proteinase, and PsaA, and their use as a vaccine component with or without PpmA. The invention also discloses the use of antibodies against said proteins for passive immunization and diagnosis.
    Type: Application
    Filed: February 15, 2012
    Publication date: November 29, 2012
    Applicant: MUCOSIS B.V.
    Inventors: Cornelis Johannes Leenhouts, Ronald de Groot, Peter Wilhelmus Maria Hermans
  • Patent number: 8142789
    Abstract: The invention relates to the field of biology, more specifically to the field of immunology and microbiology. The invention further relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in particular, the invention relates to means and methods to identify, select and isolate a vaccine component for passive and/or active immunisation against a microorganism that can be killed by opsonophagocytic cells. The invention relates to a method to identify an opsonophagocytosis inducing antigen as a vaccine component for immunisation against a microorganism. The invention describes three pneumococcal proteins SlrA, IgAl proteinase, and PsaA, and their use as a vaccine component with or without PpmA. The invention also discloses the use of antibodies against said proteins for passive immunization and diagnosis.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: March 27, 2012
    Assignee: Mucosis B.V.
    Inventors: Cornelis Johannes Leenhouts, Ronald de Groot, Peter Wilhelmus Maria Hermans
  • Patent number: 7337657
    Abstract: A pressure glow plug for a diesel engine has a glow plug body 2 for being inserted into a cylinder of the diesel engine, a heating rod 1 that is arranged in the glow plug body 2 and a pressure sensor 9 that is arranged between the heating rod 1 and the glow plug body 2 in such a way that the pressure in the combustion chamber of the cylinder that is transmitted by the heating rod 1 influences the pressure sensor 9. The heating rod 1 is arranged in the glow plug body 2 such that it can be displaced in an axially sliding fashion, namely by a corresponding sliding element, for example, a membrane 7 or seals 3.
    Type: Grant
    Filed: September 20, 2004
    Date of Patent: March 4, 2008
    Assignees: Beru AG, Texas Instruments Holland B.V.
    Inventors: Michael Haussner, Ulf Wyrwich, Hans Houben, Frank Pechhold, Heinz-Georg Schmitz, Dirk Von Hacht, Marc Gerard Johan Borgers, Albert Ferdinand Zwijze, Paulus Thomas Johannes Gennissen, Ronald De Groot, Arie-Jan Koelling
  • Publication number: 20070082003
    Abstract: The invention relates to the field of biology, more specifically to the field of immunology and microbiology. The invention further relates to the field of vaccines against microbial infections and especially bacterial vaccines, in particular to pneumococcal vaccines. More in particular, the invention relates to means and methods to identify, select and isolate a vaccine component for passive and/or active immunisation against a microorganism that can be killed by opsonophagocytic cells. The invention relates to a method to identify an opsonophagocytosis inducing antigen as a vaccine component for immunisation against a microorganism. The invention describes three pneumococcal proteins SlrA, IgAl proteinase, and PsaA, and their use as a vaccine component with or without PpmA. The invention also discloses the use of antibodies against said proteins for passive immunization and diagnosis.
    Type: Application
    Filed: May 17, 2004
    Publication date: April 12, 2007
    Inventors: Cornelis Leenhouts, Ronald de Groot, Peter Hermans