Patents by Inventor Ronald E. White
Ronald E. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8485190Abstract: A seal and a respiraoty mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance. In one embodiment, the seal includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal in this embodiment is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: GrantFiled: December 13, 2010Date of Patent: July 16, 2013Assignee: RIC Investments, LLCInventors: Shari S. Barnett, Kristine K. Sabo, Eugene N. Scarberry, Ronald E. White, Benedict R. McElroy, Virginia A. Handke
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Patent number: 8141682Abstract: A first embodiment of the security apparatus comprises a retaining collar; a plurality of segments forming a generally frusta-conical enclosure, with one or more of the segments having an access opening therein; and a lockable access door covering the opening. The retaining collar is separable into portions that conforms to the shape of the periphery and are coupled together around the structure. The segments have an upper portion that attaches to the collar; and have a bottom portion that extends radically downwardly from the collar at an angle of about 30 degree; with the radial edges interconnected forming the enclosure. A second embodiment of the apparatus secures a ladder supported on a wall and a retaining bar; a plurality of segments forming a generally semi-frusta-conical enclosure, with one or more of the segments having an access opening therein; and a lockable access door covering the opening.Type: GrantFiled: August 3, 2009Date of Patent: March 27, 2012Inventor: Ronald E. White
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Publication number: 20110088698Abstract: A seal and a respiraoty mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance. In one embodiment, the seal includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal in this embodiment is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: ApplicationFiled: December 13, 2010Publication date: April 21, 2011Applicant: RIC INVESTMENTS, LLCInventors: SHARI S. BARNETT, PATRICK M. HANDKE, KRISTINE K. SABO, EUGENE N. SCARBERRY, RONALD E. WHITE, BENEDICT R. McELROY, VIRGINA A. HANDKE
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Patent number: 7870859Abstract: A seal and a respiraoty mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance. In one embodiment, the seal includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal in this embodiment is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: GrantFiled: February 4, 2005Date of Patent: January 18, 2011Assignee: RIC Investments, LLCInventors: Shari S. Barnett, Patrick M. Handke, Virgina A. Handke, legal representative, Kristine K. Sabo, Eugene N. Scarberry, Ronald E. White, Benedict R. McElroy
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Publication number: 20100291034Abstract: Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations comprising, separately or together: (a) a CYP3A4 inhibitor; and (b) a HCV protease inhibitor; for concurrent or consecutive administration in treating a human subject infected with HCV.Type: ApplicationFiled: July 19, 2010Publication date: November 18, 2010Applicant: Schering CorporationInventors: Robert O RALSTON, II, Julie M. Strizki, Jaromir Vlach, Samir K. Gupta, Edward M. O'Mara, JR., Anima Ghosal, Michelle A. Treitel, James F. McLeod, Ronald E. White
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Publication number: 20100025150Abstract: A first embodiment of the security apparatus comprises a retaining collar; a plurality of segments forming a generally frusta-conical enclosure, with one or more of the segments having an access opening therein; and a lockable access door covering the opening. The retaining collar is separable into portions that conforms to the shape of the periphery and are coupled together around the structure. The segments have an upper portion that attaches to the collar; and have a bottom portion that extends radically downwardly from the collar at an angle of about 30 degree; with the radial edges interconnected forming the enclosure. A second embodiment of the apparatus secures a ladder supported on a wall and a retaining bar; a plurality of segments forming a generally semi-frusta-conical enclosure, with one or more of the segments having an access opening therein, and a lockable access door covering the opening.Type: ApplicationFiled: August 3, 2009Publication date: February 4, 2010Inventor: Ronald E. White
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Publication number: 20080029340Abstract: A first embodiment of the security apparatus comprises a retaining collar, a plurality of segments forming a generally frusta-conical enclosure, with one or more of the segments having an access opening therein; and a lockable access door covering the opening. The retaining collar is separable into portions that conforms to the shape of the periphery and are coupled together around the structure. The segments have an upper portion that attaches to the collar; and have a bottom portion that extends radially downwardly from the collar at an angle of about 30 degree; with the radial edges interconnected forming the enclosure. A second embodiment of the apparatus secures a ladder supported on a wall, and a retaining bar; a plurality of segments forming a generally semi-frusta-conical enclosure, with one or more of the segments having an access opening therein; and a lockable access door covering the opening.Type: ApplicationFiled: August 4, 2006Publication date: February 7, 2008Inventor: Ronald E. White
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Patent number: 6895965Abstract: A seal and a mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance and a second portion associated with the first portion. The second portion includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: GrantFiled: March 26, 2002Date of Patent: May 24, 2005Assignee: Respironics, Inc.Inventors: Eugene N. Scarberry, Ronald E. White, Benedict R. McElroy
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Publication number: 20020100479Abstract: A seal and a mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance and a second portion associated with the first portion. The second portion includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: ApplicationFiled: March 26, 2002Publication date: August 1, 2002Applicant: Respironics, Inc.Inventors: Eugene N. Scarberry, Ronald E. White, Benedict R. McElroy
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Patent number: 6397847Abstract: A seal and a mask having a seal adapted for confronting engagement with a surface of a user to form an interface therewith. The seal includes a first portion defined by a gel substance and a second portion associated with the first portion. The second portion includes a selectively formable substance adapted to be molded from a first pattern into a second pattern and to retain the second pattern responsive to being so molded. The seal and mask having the seal is tailored to patient by causing the formable portion of the seal to be placed in a malleable state, applying the seal to the patient while the formable portion is in the malleable state, and causing the formable portion to be placed in a fixed state to retain a shape generally conforming to the portion of the patient underlying the seal.Type: GrantFiled: September 1, 1999Date of Patent: June 4, 2002Assignee: Respironics, Inc.Inventors: Eugene N. Scarberry, Ronald E. White, Benedict R. McElroy
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Patent number: 5637580Abstract: Compounds of structure: ##STR1## as well as their pharmaceutically-acceptable salts and biohydrolyzables esters, and hydrates thereof, are effective antiinfective agents, useful in treating and preventing infection.Type: GrantFiled: June 7, 1995Date of Patent: June 10, 1997Assignee: The Procter & Gamble CompanyInventors: Ronald E. White, Thomas P. Demuth, Jr.
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Patent number: 5631256Abstract: Antimicrobial quinolone thiourea compounds of the general formula: ##STR1## wherein (1) A.sup.1, A.sup.2, A.sup.3, R.sup.1, R.sup.3, R.sup.4, and R.sup.6 form any of a variety of quinolone and related heterocyclic structures similar to those known in the art to have antimicrobial activity; and(2) (1) R.sup.1 is X, R.sup.3 is X, or both R.sup.1 and R.sup.3 are X; and X is the thiourea containing moietyand pharmaceutically-acceptable salts and biohydrolyzable esters thereof, and hydrates thereof.Type: GrantFiled: April 8, 1994Date of Patent: May 20, 1997Assignee: The Procter & Gamble CompanyInventors: Thomas P. Demuth, Jr., Ronald E. White
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Patent number: 5530116Abstract: Antimicrobial quinolonyl lactam compounds comprising a lactam-containing moiety linked to a quinolone moiety, of the formula: ##STR1## wherein (1) A.sup.1, A.sup.2, A.sup.3, R.sup.1, and R.sup.4 generally form any of a variety of quinolone, naphthyridine or related cyclic moieties known in the art to have antimicrobial activity; and(2) R.sup.6 is part of a linking moiety, linking the quinolone moiety to a lactam-containing moiety having the formula: ##STR2## wherein (3) R.sup.10, R.sup.11, R.sup.12, R.sup.13, and R.sup.Type: GrantFiled: December 22, 1994Date of Patent: June 25, 1996Assignee: The Procter & Gamble CompanyInventors: Thomas P. Demuth, Jr., Ronald E. White
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Patent number: 5491139Abstract: Antimicrobial quinolonyl lactam compounds comprising a lactam-containing moiety linked, by a non-ester linking moiety, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: ##STR1## wherein (1) R.sup.3, R.sup.4, and R.sup.5, together with bonds "a" and "b", form any of a variety of lactam-containing moieties similar to those known in the art to have antimicrobial activity;(2) A, R.sup.6, R.sup.7, and R.sup.8 form any of a variety of quinolone or naphthyridine structures similar to those known in the art to have antimicrobial activity; and(3) Y, together with R.sup.5, form a variety of non-ester linking moieties between the lactam-containing moiety and the quinolone moiety.Type: GrantFiled: April 6, 1994Date of Patent: February 13, 1996Assignee: The Procter & Gamble CompanyInventors: Thomas P. Demuth, Jr., Ronald E. White
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Patent number: 5457430Abstract: Optical pumping devices use light reflected from reflecting surfaces to provide a portion of the light incident on the photodetector. Conventional optical pumping devices experience a decay, over time, of the initial light intensity incident on the photodetector. The optical pumping device of the invention experiences reduced light intensity decay. The invention passivates the reflecting surfaces to eliminate tarnish and oxidation by pretarnishing the surfaces or covering the surfaces with a material whose reflectivity does not vary over time, such as gold.Type: GrantFiled: November 10, 1994Date of Patent: October 10, 1995Assignee: Ball CorporationInventors: Thomas C. English, Funming Li, Ronald E. White, James A. Carmichael
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Patent number: 5387748Abstract: Antimicrobial dithiocarbamoyl quinolone compounds of the general formula: ##STR1## wherein (1) A.sup.1, A.sup.2, A.sup.3, R.sup.1, R.sup.3, R.sup.4, and R.sup.6 form any of a variety of quinolone and related heterocyclic structures similar to those known in the art to have antimicrobial activity; and(2)(1) R.sup.1 is X, R.sup.3 is X, or both R.sup.1 and R.sup.3 are X; and(2) X is --R.sup.15 --N(R.sup.16)(R.sup.17) or --R.sup.15 --R.sup.18 --N(R.sup.19)(R.sup.17), where(a)(1) R.sup.15 is nil, alkyl, a carbocyclic ring, or a heterocyclic ring; and(2) R.sup.16 is hydrogen; alkyl; alkenyl; a carbocyclic ring; a heterocyclic ring; or(3) when X is R.sup.15 --N(R.sup.16)(R.sup.17), R.sup.16 and R.sup.15 may together comprise a heterocyclic ring including the nitrogen atom to which R.sup.15 and R.sup.16 are bonded;(b) R.sup.17 is C(.dbd.S)--S--M, where M is a pharmaceutically-acceptable salt or biohydrolyzable ester; and(c)(1) R.sup.18 is alkyl, a carbocyclic ring, or a heterocyclic ring; and(2) R.sup.Type: GrantFiled: May 2, 1991Date of Patent: February 7, 1995Assignee: Procter & Gamble Pharmaceuticals, Inc.Inventors: Thomas P. Demuth, Jr., Ronald E. White
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Patent number: 5328908Abstract: Antimicrobial quinolone thiourea compounds of the general formula: ##STR1## wherein (1) A.sup.1, A.sup.2, A.sup.3, R.sup.1, R.sup.3, R.sup.4, and R.sup.6 form any of a variety of quinolone and related heterocyclic structures similar to those known in the art to have antimicrobial activity; and(2)(1) R.sup.1 is X, R.sup.3 is X, or both R.sup.1 and R.sup.3 are X; and(2) X is --R.sup.15 --N(R.sup.16)(R.sup.17) or --R.sup.15 --R.sup.18 --N(R.sup.19)(R.sup.17), where(a)(1) R.sup.15 is nil, alkyl, a carbocyclic ring, or a heterocyclic ring; and(2) R.sup.16 is hydrogen; alkyl; alkenyl; a carbocyclic ring; a heterocyclic ring; or(3) when X is R.sup.15 --N(R.sup.16)(R.sup.17), R.sup.16 and R.sup.15 may together comprise a heterocyclic ring including the nitrogen atom to which R.sup.15 and R.sup.16 are bonded;(b) R.sup.17 is C(.dbd.S)--NR.sup.20 R.sup.21 ; where R.sup.20 is, hydrogen, alkyl, alkenyl, a carbocyclic ring or a heterocyclic ring; and R.sup.21 is R.sup.20 or N(R.sup.20)(R.sup.20); or R.sup.20 and R.sup.Type: GrantFiled: April 20, 1990Date of Patent: July 12, 1994Assignee: Procter & Gamble Pharmaceuticals, Inc.Inventors: Thomas P. Demuth, Jr., Ronald E. White
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Patent number: 5281703Abstract: The present invention provides methods of making compounds of the structure[Q-L.sup.1 ]-L-[L.sup.2 -B[wherein(I) Q is a quinolone moiety;(II) B is a beta-lactam moiety;(III) L, L.sup.1, and L.sup.2 together comprise a carbamate-containing linking moietycomprising the steps of:(1) Reacting a lactam compound of the formula B-L.sup.4 -H with phosgene to form an intermediate compound of the formula B--L.sup.4 --C(=O)--Cl, where L.sup.4 is oxygen; and(2) Coupling said intermediate compound with a quinolone compound of the formula Q-L.sup.3 -R.sup.44 ; wherein L.sup.3 is nitrogen; R.sup.44 is hydrogen, Si(R.sup.45).sub.3, or Sn(R.sup.45).sub.3 ; and R.sup.45 is lower alkyl.Preferably, the process additionally comprises steps prior to the reacting and coupling steps where esters of the lactam and quinolone compounds are made. Also preferably, the coupling step comprises adding a solution containing the quinolone compound to a solution containing the intermediate compound.Type: GrantFiled: May 7, 1993Date of Patent: January 25, 1994Assignee: Procter & Gamble Pharmaceuticals, Inc.Inventors: Ronald E. White, Thomas P. Demuth, Jr.
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Patent number: 5273973Abstract: Antimicrobial quinolnyl lactam esters comprising a lactam-containing moiety linked, by an ester group, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: ##STR1## wherein (1) R.sup.3, R.sup.4, and R.sup.5, together with bonds "a" and "b", form certain lactam-containing moieties similar to those known in the art to have antimicrobial activity; and(2) A, R.sup.6, R.sup.7, and R.sup.8 form any of a variety of quinolone or napthyridine structures similar to those known in the art to have antimicrobial activity.Type: GrantFiled: August 21, 1992Date of Patent: December 28, 1993Assignee: Norwich Eaton Pharmaceuticals, Inc.Inventors: Ronald E. White, Thomas P. Demuth, Jr.
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Patent number: 5180719Abstract: Antimicrobial quinolonyl lactam esters comprising a lactam-containing moiety linked, by an ester group, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: ##STR1## wherein (1) R.sup.3, R.sup.4, and R.sup.5, together with bonds "a" and "b", form certain lactam-containing moieties similar to those known in the art to have antimicrobial activity; and(2) A.sup.2, A.sup.2, A.sup.3, R.sup.7, R.sup.8, and R.sup.9 form any of a variety of quinolone or naphthyridine structures similar to those known in the art to have antimicrobial activity.Type: GrantFiled: April 29, 1991Date of Patent: January 19, 1993Assignee: Norwich Eaton Pharmaceuticals, Inc.Inventors: Ronald E. White, Thomas P. Demuth, Jr.