Patents by Inventor Ronald G. Powles

Ronald G. Powles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1H-pyrazole-1-(branched)alkanamides as antiarrhythmic agents, compositions and use
    Patent number: 4988725
    Abstract: N-[(alkylamino)alkyl]-3,4(or 4,5)-diaryl-1H-pyrazole-1-(branched)alkanamides and pyrazole-1-alkanamines useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic acid with an appropriate diamine followed by reduction or by reacting the anion of a lower-alkyl ester of a pyrazole-1-acetic acid with an alkylating agent followed by displacement of the ester by an appropriate amine.
    Type: Grant
    Filed: December 28, 1989
    Date of Patent: January 29, 1991
    Assignee: Sterling Drug Inc.
    Inventors: Denis M. Bailey, Ronald G. Powles
  • 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use
    Patent number: 4916150
    Abstract: N-[alkylamino)alkyl]-3,4(or 4,5)-diaryl-1H-pyrazole-1-(branched)alkanamides and pyrazole-1-alkanamines useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic acid with an appropriate diamine followed by reduction or by reacting the anion of a lower-alkyl ester of a pyrazole-1-acetic acid with an alkylating agent followed by displacement of the ester by an appropriate amine.
    Type: Grant
    Filed: March 22, 1989
    Date of Patent: April 10, 1990
    Assignee: Sterling Drug Inc.
    Inventors: Denis M. Bailey, Ronald G. Powles