Patents by Inventor Ronald G. Schoner

Ronald G. Schoner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to produce recombinant proteins using an expression vector comprising transcriptional and translational activating sequences
    Patent number: 5192669
    Abstract: The present invention is composed of novel recombinant DNA expression vectors which contain a transcriptional activating sequence, a translational activating sequence and a DNA sequence coding for a functional polypeptide, especially bovine growth hormone. The aforementioned translational activating sequences contain a ribosome binding site and are designed to provide high level expression of DNA that codes for virtually any functional polypeptide. The invention further provides transformed microbial host cells capable of producing bovine growth hormone and other functional polypeptides at high levels.
    Type: Grant
    Filed: August 13, 1991
    Date of Patent: March 9, 1993
    Assignee: Eli Lilly and Company
    Inventors: Brigitte E. Schoner, Ronald G. Schoner
  • Recombinant DNA expression vector comprising both transcriptional and translational activating sequences
    Patent number: 5063158
    Abstract: The present invention is composed of novel recombinant DNA expression vectors which contain a transcriptional activating sequence, a translational activating sequence and a DNA sequence coding for a functional polypeptide, especially bovine growth hormone. The aforementioned translational activating sequences contain a ribosome binding site and are designed to provide high level expression of DNA that codes for virtually any functional polypeptide. The invention further provides transformed microbial host cells capable of producing bovine growth hormone and other functional polypeptides at high levels.
    Type: Grant
    Filed: December 12, 1989
    Date of Patent: November 5, 1991
    Assignee: Eli Lilly and Company
    Inventors: Brigitte E. Schoner, Ronald G. Schoner
  • Plasmid for foreign gene expression in B. subtilis
    Patent number: 4585739
    Abstract: The invention provides a mutant plasmid useful for introducing into B. subtilis foreign DNA, the nucleic acid sequence of which codes for production of a desired product. The plasmid is constructed from (1) a segment of B. pumllus DNA containing a chloramphenicol acetyltransferase gene plus an EcoRI* promoter fragment cloned from phage SPO2 DNA and a (2) portion of a B. subtilis plasmid, pUB110. The plasmid gives enhanced expression of genes coding for certain products, such as dihydrofolate reductase.
    Type: Grant
    Filed: March 7, 1983
    Date of Patent: April 29, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul S. Lovett, Ronald G. Schoner