Abstract: A stable topical alcohol-free aerosol foam containing one or more keratolytic agents is provided. The foam-forming formulation is an emulsion which contains an HFA propellant and one or more keratolytic agents. The emulsion has an oil phase and an aqueous, i.e. water-containing, phase. The active agent(s) may be present in either phase of the emulsion or dispersed in the emulsion. The oil phase may consist at least in part of the HFA propellant. Either or both of the oil phase and the aqueous phase may contain one or more surfactants, emulsifiers, emulsion stabilizers, buffers, and/or other excipients. The foam is stable on the skin, for example, for at least 5 minutes at body temperature, preferably at least 20 minutes at body temperature, and disappears into the skin upon rubbing or after prolonged standing. In one embodiment, the formulation contains an HFA propellant which does not contain additional co-solvents or co-propellants.

Abstract: Aerosol spray formulations capable of delivering high concentrations of active agent-containing materials and/or excipient are described herein. The formulation contains a carrier fluid, a propellant, and a therapeutic, prophylactic, consmeticeutical and/or inert solid suspended, dissolved, or dispersed in the formulation. The active ingredient may be any pharmaceutically active agent, but is preferably an antibiotic, an antihistamine, an anesthetic, an anti-inflammatory, and/or an astringent. In one embodiment, the active agent is an antifungal agent. In another embodiment, the active agent is a consmeticeutical. The active agent can optionally be dispersed on, or associated with, a carrier powder. The carrier fluid is a highly volatile silicone liquid, which evaporates in less than 10 minutes, preferably less than 5 minutes, after application of the formulation to the patient's skin.

Abstract: Tooth whitening compositions, tooth whitening films, and methods of whitening teeth are described. The tooth whitening compositions and tooth whitening films include a tooth whitening agent and a cellulose polymer of formula (I) wherein; R is H, C1-6 alkyl, (C1-6 alkylO)mR2, or —C(O)R1, wherein at least one R is H, one R is C1-6 alkyl or (C1-6 alkylO)mR2, and one R is —C(O)R1; R1 is C5-10 aryl or C1-6 alkyl, optionally substituted with at least one CO2H; R2 is H or C(O)R1; m is 1-5; and n is 2-350. The tooth whitening compositions are may be, for example, liquids or films that are applied to a tooth for a time sufficient to whiten the tooth.

Abstract: Oral care compositions are described herein. The oral care compositions generally have Theological properties that are desirable for use in a dispensing toothbrush. In some instances, the oral care composition has a yield point of y Pa and a shear slope of x Pa/Sec, wherein the ratio of yield point to shear slope is less than y/(74?370x+470x2). In some instances, the oral care composition has a Newtonian viscosity at 400 Pa of less than 1.0 Pa.s.