Patents by Inventor Ronald H. Erickson

Ronald H. Erickson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediates for making sigma binding site agents
    Patent number: 5359098
    Abstract: Sigma binding site agents having the formula ##STR1## wherein A.sup.1, A.sup.2, A.sup.3, B, y and 2 are defined in the specification, W is halogen, which are novel intermediates useful in preparing the presently binding site agents.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: October 25, 1994
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Ronald H. Erickson, Kenneth J. Natalie, Jr., Michael J. Pontecorvo, Waclaw J. Rzeszotarski
  • Sigma binding site agents
    Patent number: 5278174
    Abstract: Sigma binding site agents having the formula ##STR1## which are useful to inhibit sigma binding site-induced activity, pharmaceutical compositions including these agents, and methods of using these agents to inhibit sigma binding site-induced activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented agents.
    Type: Grant
    Filed: May 17, 1991
    Date of Patent: January 11, 1994
    Assignee: Scios Nova, Inc.
    Inventors: Ronald H. Erickson, Kenneth J. Natalie, Jr., Michael J. Pontecorvo, Waclaw J. Rzeszotarski
  • Method of treating bronchoconstriction with 1,3-unsymmetrical straight chain alkyl-substituted 8-phenylxanthines
    Patent number: 5032593
    Abstract: 1,3-Alkyl substituted-8-phenylxanthines in which the straight chain alkyl substituents are different and pharmaceutically acceptable salts of such compounds are disclosed. Preferred compounds have 1-n-propyl-3-methyl and 1-methyl-3-n-propyl substituents. The compounds are potent bronchodilators.
    Type: Grant
    Filed: July 1, 1988
    Date of Patent: July 16, 1991
    Assignee: Marion Merrell Dow Inc.
    Inventors: Waclaw J. Rzeszotarski, Ronald H. Erickson
  • 8-arylxanthines
    Patent number: 4783530
    Abstract: 1,3-alkylsubstituted-8-(3,4-,3- or 4-substituted phenyl)xanthines and pharmaceutically acceptable salts of such compounds are disclosed. The 3-substituents are hydrogen, dimethylaminomethyl, or 2,3-dihydroxypropyloxy. The 4-substituents are selected from hydroxy, cyano, --NHCON(R.sub.5).sub.2, --C(.dbd.NH)N(R.sub.5).sub.2, --NH--C(.dbd.NH)N(R.sub.5).sub.2, with each R.sub.5 independently being hydrogen or an alkyl group of one to three carbons and provided that when the 3-substituent is hydrogen the 4-substituent is not hydroxy or hydrogen.The compounds are potent adenosine receptor antagonists having relatively low lipophilicity. The compounds are intended for use as bronchodilators and cardiotonics.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: November 8, 1988
    Assignee: Marion Laboratories, Inc.
    Inventors: Waclaw J. Rzeszotarski, Rickey P. Hicks, Ronald H. Erickson