Patents by Inventor Ronald H. Reeder

Ronald H. Reeder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human RRN3 and compositions and methods relating thereto
    Patent number: 6825034
    Abstract: Polynucleotide sequences encoding eukaryotic Rrn3 polypeptides are provided. Rrn3 is a eukaryotic RNA polymerase I transcription factor. The Rrn3 polypeptides, and antibodies thereto, can be used as diagnostic tools, as therapeutic agents and to identify agonist and antagonists of Rrn3.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: November 30, 2004
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Ronald H. Reeder, Beth Moorefield, Elizabeth A. Greene
  • Human RRN3 and compositions and methods relating thereto
    Publication number: 20020090706
    Abstract: Polynucleotide sequences encoding eukaryotic Rrn3 polypeptides are provided. Rrn3 is a eukaryotic RNA polymerase I transcription factor. The Rrn3 polypeptides, and antibodies thereto, can be used as diagnostic tools, as therapeutic agents and to identify agonist and antagonists of Rrn3.
    Type: Application
    Filed: August 16, 2001
    Publication date: July 11, 2002
    Inventors: Ronald H. Reeder, Beth Moorefield, Elizabeth A. Greene
  • Polymerase I promoter plasmid and vector constructs
    Patent number: 6368862
    Abstract: rDNA promoter constructs useful in plasmids and vectors directing transcription of RNAs in a Pol I-specific manner constructed of four elements in a serial array: a first nucleotide sequence, capable of hybridizing under stringent conditions to an rDNA promoter element; a second nucleotide sequence, capable of hybridizing under stringent conditions to an internal ribosome entry signal (IRES); a third nucleotide sequence containing a coding region interest; a fourth nucleotide sequence containing a polyadenylation (polyA) signal sequence; a fifth rDNA enhancer element may be positioned upstream of the serial array. Also recombinant permissive cells and genetically engineered stable cell lines that contain the subject constructs.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: April 9, 2002
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Theodore D. Palmer, Brian M. McStay, A. Dusty Miller, Ronald H. Reeder