Patents by Inventor Ronald HAUSE

Ronald HAUSE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USES OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20250123281
    Abstract: Provided herein are uses of anti-B cell maturation antigen (BCMA) chimeric antigen receptors (CARs) for treating B-cell related conditions, such as BCMA-expressing cancers.
    Type: Application
    Filed: September 20, 2024
    Publication date: April 17, 2025
    Applicant: Celgene Corporation
    Inventors: Timothy CAMPBELL, Ronald HAUSE, Kristen HEGE, Yue JIANG, Shari KAISER, Ethan THOMPSON, Jaymes FULLER, Nathan T. MARTIN, Rong LIU, Justine DELL'ARINGA
  • High-throughput polynucleotide library sequencing and transcriptome analysis
    Patent number: 12049667
    Abstract: Provided herein are methods for target gene sequencing and single cell barcoding in conjunction with analysis of gene expression in single cells. In some embodiments, the target gene is an immune molecule, such as an antibody or TCR. In some embodiments, the methods can be used to carry out transcriptome sequencing, e.g., RNA sequencing, to capture transcriptome of single cells paired with full receptor immune receptor sequences such that information about the immune repertoire and transcriptome of a cell can be determined. Also provided are polynucleotide libraries for use in carrying out transcriptome analysis and immune molecule, e.g., antibody or TCR, sequencing.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: July 30, 2024
    Assignee: ABvitro LLC
    Inventors: Stephen Jacob Goldfless, Adrian Wrangham Briggs, Rajagopal Chari, Yue Jiang, Ronald Hause, Francois Vigneault
  • METHODS AND COMPOSITIONS FOR THE MOLECULAR DIAGNOSIS OF MICROSATELLITE INSTABILITY AND TREATMENTS FOR CANCER
    Publication number: 20230317206
    Abstract: Described herein are methods and compositions related to treatments for cancer. Various embodiments relate to the determination of microsatellite instability as a marker for the likelihood of whether a given cancer will respond to certain therapies, including checkpoint inhibitor immunotherapies, and methods of treatment based upon those determinations.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 5, 2023
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Stephen J. SALIPANTE, Adam S. WAALKES, Dustin LONG, Ronald HAUSE
  • USES OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20210128619
    Abstract: Provided herein are uses of anti-B cell maturation antigen (BCMA) chimeric antigen receptors (CARs) for treating B-cell related conditions, such as BCMA-expressing cancers.
    Type: Application
    Filed: November 4, 2020
    Publication date: May 6, 2021
    Applicants: CELGENE CORPORATION, JUNO THERAPEUTICS, INC., BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Timothy CAMPBELL, Ronald HAUSE, Kristen HEGE, Yue JIANG, Shari KAISER, Ethan THOMPSON, Jaymes FULLER, Nathan MARTIN, Rong LIU, Justine DELL'ARINGA
  • HIGH-THROUGHPUT POLYNUCLEOTIDE LIBRARY SEQUENCING AND TRANSCRIPTOME ANALYSIS
    Publication number: 20200354784
    Abstract: Provided herein are methods for target gene sequencing and single cell barcoding in conjunction with analysis of gene expression in single cells. In some embodiments, the target gene is an immune molecule, such as an antibody or TCR. In some embodiments, the methods can be used to carry out transcriptome sequencing, e.g., RNA sequencing, to capture transcriptome of single cells paired with full receptor immune receptor sequences such that information about the immune repertoire and transcriptome of a cell can be determined. Also provided are polynucleotide libraries for use in carrying out transcriptome analysis and immune molecule, e.g., antibody or TCR, sequencing.
    Type: Application
    Filed: May 25, 2018
    Publication date: November 12, 2020
    Applicant: AbVitro LLC
    Inventors: Stephen Jacob GOLDFLESS, Adrian Wrangham BRIGGS, Rajagopal CHARI, Yue JIANG, Ronald HAUSE, Francois VIGNEAULT