Patents by Inventor Ronald I. Swanstrom

Ronald I. Swanstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and uses for molecular tags
    Patent number: 11177020
    Abstract: Methods and uses for molecular tags are disclosed. Molecular tags may be attached to nucleic acid molecules. The attachment of the nucleic acid molecules prior to PCR amplification and sequencing improves the accuracy of genetic analysis and detection of genetic variations and diversity. Molecular tags may also be used for detection of drug-resistant variants. Methods for using molecular tags for determining and correcting PCR errors and/or sequencing error are also disclosed.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 16, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Cassandra B. Jabara, Jeffrey A. Anderson, Ronald I. Swanstrom
  • METHODS AND USES FOR MOLECULAR TAGS
    Publication number: 20160026758
    Abstract: Methods and uses for molecular tags are disclosed. Molecular tags may be attached to nucleic acid molecules. The attachment of the nucleic acid molecules prior to PCR amplification and sequencing improves the accuracy of genetic analysis and detection of genetic variations and diversity. Molecular tags may also be used for detection of drug-resistant variants. Methods for using molecular tags for determining and correcting PCR errors and/or sequencing error are also disclosed.
    Type: Application
    Filed: February 27, 2013
    Publication date: January 28, 2016
    Inventors: Cassandra B. Jabara, Jeffrey A. Anderson, Ronald I. Swanstrom
  • Method of inhibiting retroviral integrase
    Patent number: 6815461
    Abstract: Disclosed is a method of inhibiting retroviral integrase in a subject in need of such treatment. The method comprises administering to the subject an effective retroviral integrase inhibiting amount of a bis-benzimidazole compound such as bis[5-amidino-2-benzimidazolyl]methane, 1,2-bis[5-amidino-2-benzimidazolyl]ethane, 1,2-bis[5-amidino-2-benzimidazolyl]ethene or a pharmaceutically acceptable salt thereof. A method for combatting retroviral infections is also disclosed.
    Type: Grant
    Filed: January 20, 1994
    Date of Patent: November 9, 2004
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Christine C. Dykstra, Ronald I. Swanstrom, Richard R. Tidwell